Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meclofenamate sodium
Drug ID BADD_D01363
Description A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Indications and Usage For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
Marketing Status Prescription; Discontinued
ATC Code M01AG04; M02AA18
DrugBank ID DB00939
KEGG ID D00169
MeSH ID D008469
PubChem ID 4038
TTD Drug ID D08IFL
NDC Product Code 0378-2150; 38779-0237; 63126-301; 22568-1018; 49452-4397; 0378-3000
Synonyms Meclofenamic Acid | Meclofenamate Sodium Anhydrous | Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, monosodium salt, monohydrate | Meclofenamate Sodium | Sodium Meclofenamate | Meclofenamate, Sodium | Meclofenamate Sodium Monohydrate | Meclofenamate | Meclomen
Chemical Information
Molecular Formula C14H10Cl2NNaO2
CAS Registry Number 6385-02-0
SMILES CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)[O-])Cl.[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Asthenia08.01.01.001--Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Colitis07.08.01.001--
Colour blindness06.02.09.001; 03.01.01.001--Not Available
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Depression19.15.01.001--
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Eosinophilia01.02.04.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Erythema nodosum23.07.02.001; 10.02.01.020--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematocrit decreased13.01.05.001--Not Available
Haemoglobin13.01.05.018--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Ileus paralytic07.02.05.001--Not Available
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