Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Drug dependence
ADR ID BADD_A01328
ADR Hierarchy
19      Psychiatric disorders
19.07      Psychiatric disorders NEC
19.07.02      Substance-related disorders
19.07.02.009      Drug dependence
Description Disorders related to substance abuse. [MeSH]
MedDRA Code 10013663
MeSH ID D019966; D002189; D019966; D019966; D019970; D019966; D019966; D006556; D019966; D000074607; D019966; D019966; D058999
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Addicted to amphetamine | Addicted to cocaine | Addicted to drugs | Addicted to heroin | Addiction any drug | Addiction to drugs | Addiction to drugs (excl drug psychosis) | Amphetamine and other psychostimulant dependence | Amphetamine and other psychostimulant dependence, continuous use | Amphetamine and other psychostimulant dependence, episodic use | Amphetamine and other psychostimulant dependence, in remission | Amphetamine and other psychostimulant dependence, unspecified use | Amylobarbitone dependency | Barbiturate and similarly acting sedative or hypnotic | Barbiturate and similarly acting sedative or hypnotic dependence | Barbiturate and similarly acting sedative or hypnotic dependence, continuous use | Barbiturate and similarly acting sedative or hypnotic dependence, episodic use | Barbiturate and similarly acting sedative or hypnotic dependence, in remission | Barbiturate and similarly acting sedative or hypnotic dependence, unspecified use | Barbiturate dependency | Benzodiazepine dependent | Cannabis addiction | Cannabis dependence | Cannabis dependence, continuous use | Cannabis dependence, episodic use | Cannabis dependence, in remission | Cannabis dependence, unspecified use | Cocaine addiction | Cocaine dependence | Cocaine dependence, continuous use | Cocaine dependence, episodic use | Cocaine dependence, in remission | Cocaine dependence, unspecified use | Combinations of drug dependence excluding morphine type drug | Combinations of drug dependence excluding opioid type drug | Combinations of drug dependence excluding opioid type drug, continuous use | Combinations of drug dependence excluding opioid type drug, episodic use | Combinations of drug dependence excluding opioid type drug, in remission | Combinations of drug dependence excluding opioid type drug, unspecified use | Combinations of morphine type drug with any other drug dependence | Combinations of opioid type drug with any other drug dependence | Combinations of opioid type drug with any other drug dependence, continuous use | Combinations of opioid type drug with any other drug dependence, episodic use | Combinations of opioid type drug with any other drug dependence, in remission | Combinations of opioid type drug with any other drug dependence, unspecified use | Dependence addictive | Dependence drug (NOS) | Dependence non-addictive | Dependence on amphetamines | Dependence on barbiturates | Dependence on cannabis | Dependence on cocaine | Dependence on hallucinogens | Dependence on marijuana | Dependence on opiates | Dependence on tranquillisers | Dependence on volatile nitrites | Dependence on volatile solvents | Dependence psychological | Drug addiction | Drug dependence | Drug dependence NOS | Drug dependence of barbiturate type | Drug dependence of morphine type | Drug dependence physical | Drug dependence psychic | Drug dependence, unspecified | Drug habit | Drug habituating | Hallucinogen dependence | Hallucinogen dependence, continuous use | Hallucinogen dependence, episodic use | Hallucinogen dependence, in remission | Hallucinogen dependence, unspecified use | Heroin addiction | Opioid type dependence | Opioid type dependence, continuous use | Opioid type dependence, episodic use | Opioid type dependence, in remission | Opioid type dependence, unspecified use | Opium addiction | Other specified drug dependence | Other specified drug dependence, continuous use | Other specified drug dependence, episodic use | Other specified drug dependence, in remission | Other specified drug dependence, unspecified use | Unspecified drug dependence | Unspecified drug dependence, continuous use | Unspecified drug dependence, episodic use | Unspecified drug dependence, in remission | Unspecified drug dependence, unspecified use | Drug craving | Drug seeking behavior | Dependence on tranquillizers | Drug seeking behaviour | Opiate dependency relapse | Analgesic drug dependence | Polydrug dependence | Substance-Related Disorders | Drug Abuse
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Adenosine receptor A1P30542T92072
Bifunctional epoxide hydrolase 2P34913T35734
Mu-type opioid receptorP35372T47768
Protein kinase C delta typeQ05655T44861
Solute carrier family 2, facilitated glucose transporter member 1P11166T89458
Solute carrier family 2, facilitated glucose transporter member 4P14672T67658
Urokinase-type plasminogen activatorP00749T17758
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00032Acetylcysteine0.000969%
BADD_D00066Alendronic acid--
BADD_D00067Alfentanil--
BADD_D00085Alprazolam0.012164%
BADD_D00121Amlodipine--
BADD_D00165Aripiprazole--
BADD_D00167Armodafinil0.004562%
BADD_D00181Atomoxetine hydrochloride--
BADD_D00195Azathioprine--
BADD_D00209Baclofen--
BADD_D00310Buprenorphine0.112442%
BADD_D00312Bupropion0.000441%
BADD_D00325Butorphanol tartrate--
BADD_D00329Cabergoline0.022020%
BADD_D00356Carbamazepine0.009682%
BADD_D00370Carisoprodol0.001728%
BADD_D00417Cetirizine0.000086%
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00475Citalopram0.000163%
BADD_D00476Citalopram hydrobromide--
BADD_D00488Clobazam--
BADD_D00499Clomipramine0.008855%
BADD_D00501Clonazepam0.000905%
BADD_D00507Clorazepic acid0.004718%
BADD_D00509Clotrimazole0.000689%
BADD_D00621Desvenlafaxine0.002538%
BADD_D00623Dexamethasone--
BADD_D00624Dexamethasone phosphate--
BADD_D00637Dextroamphetamine sulfate--
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