Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alfentanil
Drug ID BADD_D00067
Description A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Indications and Usage For the management of postoperative pain and the maintenance of general anesthesia.
Marketing Status Prescription
ATC Code N01AH02
DrugBank ID DB00802
KEGG ID D07122
MeSH ID D015760
PubChem ID 51263
TTD Drug ID D0G5QB
NDC Product Code Not Available
Synonyms Alfentanil | Alfentanyl | Alfentanil Hydrochloride | R-39209 | R 39209 | R39209 | Alfenta | Limifen | Rapifen | Fanaxal
Chemical Information
Molecular Formula C21H32N6O3
CAS Registry Number 71195-58-9
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Anaesthetic complication neurological17.02.10.015; 12.02.12.009--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Apnoea22.02.01.001--
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Carbon dioxide increased13.02.01.011--Not Available
Cardiac arrest02.03.04.001--
Chills15.05.03.016; 08.01.09.001--
Confusional state19.13.01.001; 17.02.03.005--
Cough22.02.03.001--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis atopic10.01.04.004; 23.03.04.016--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Drug dependence19.07.02.009--Not Available
Dyskinesia17.01.02.006--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Eye disorder06.08.03.001--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
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