Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bisacodyl
Drug ID BADD_D00276
Description Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Indications and Usage Indicated for cleansing of the colon as a preparation for colonoscopy in adults.
Marketing Status Not Available
ATC Code A06AB02; A06AG02
DrugBank ID DB09020
KEGG ID D00245
MeSH ID D001726
PubChem ID 2391
TTD Drug ID D07IEF
NDC Product Code 56062-676; 49706-0650; 67091-286; 41163-607; 63868-572; 11822-0327; 58793-002; 41250-191; 49348-032; 61876-0002; 0363-6760; 46122-529; 53943-805; 43749-460; 63868-573; 70518-2976; 36800-676; 41250-665; 24385-903; 53943-676; 63941-120; 36800-327; 68210-0312; 71399-8460; 36800-120; 70795-1010; 37205-298; 68016-084; 63868-908; 63941-190; 33992-0327; 50804-190; 30142-827; 70518-1864; 51927-0115; 11822-7850; 62011-0403; 63940-327; 68998-232; 68210-4106; 37808-327; 71335-1531; 57648-002; 0904-6407; 71335-1754; 0363-3011; 62011-0277; 49035-327; 0132-0703; 55910-190; 16990-010; 49483-003; 59779-107; 69846-140; 11822-0676; 41167-0290; 30142-191; 59779-676; 55301-676; 59779-327; 55910-327; 70000-0444; 0536-3381; 11673-116; 67091-385; 70000-0221; 57896-444; 70518-3238; 57896-441; 63868-209; 71335-2010; 0363-0327; 70000-0573; 62485-036; 37205-128; 55319-195; 38779-3146; 68784-102; 68998-226; 71335-1750; 46994-327; 55910-120; 72701-102; 68016-688; 41167-0101; 67091-215; 68163-116; 50090-5385; 37808-676; 80136-871; 70518-2997; 55154-6897; 12828-0015; 41226-003; 71610-453; 68998-398; 0904-7142; 67544-655; 61715-039; 70000-0228; 68210-1022; 30142-067; 72476-845; 81440-102; 41163-195; 10237-906; 46122-608; 59779-706; 58980-415; 50804-327; 42507-190; 56062-327; 63940-676; 41250-339; 69842-816; 21130-327; 41226-151; 41167-0200; 11673-053; 55319-607; 41167-0400; 41250-676; 12579-228; 69842-089; 63868-328; 55910-848; 76457-003; 12579-230; 68210-3120; 55319-676; 41415-116; 50844-327; 36800-190; 71890-330; 70000-0538; 41167-0210; 50804-120; 46122-429; 76470-011; 72476-654; 50844-697; 0904-6748; 69617-008; 49035-607; 69168-226; 68016-197; 49035-706; 21130-676; 55910-457; 55910-253; 11673-151; 41520-019; 0574-7050; 69618-058; 37808-877; 71610-219; 61715-038; 55319-327; 21130-827; 70000-0570; 55910-954; 41415-121
Synonyms Bisacodyl | Durolax | Apo-Bisacodyl | Apo Bisacodyl | Bekunis Bisacodyl | Bisacodyl, Bekunis | Bicol | Bisac-Evac | Bisac Evac | Bisacodyl Tannex | Tannex, Bisacodyl | Bisacodyl Uniserts | Uniserts, Bisacodyl | Ulcolax | Bisalax | Bisco-Lax | Bisco Lax | Lünolax | Bisco-Zitron | Bisco Zitron | Dulcolax | Dulco-Lax | Dulco Lax | Fleet Bisacodyl | Bisacodyl, Fleet | Laxagetten | Laxanin | Laxans-ratiopharm | Laxans ratiopharm | Laxbene | Laxysat Bürger | Florisan N | ratio-Bisacodyl | ratio Bisacodyl | Dulco-lax perles | Dulco lax perles | Dulcolax perles | Rytmil | Agaroletten
Chemical Information
Molecular Formula C22H19NO4
CAS Registry Number 603-50-9
SMILES CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Abdominal rigidity07.01.05.011--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Colitis07.08.01.001--
Dehydration14.05.05.001--
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Loss of consciousness17.02.04.004--Not Available
Muscle spasms15.05.03.004--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Shock24.06.02.002--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Vomiting07.01.07.003--
Malnutrition14.03.02.004--Not Available
Bowel movement irregularity07.02.03.003--Not Available
Anorectal discomfort07.03.03.003--Not Available
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