Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram hydrobromide
Drug ID BADD_D00476
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression. Off-label indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label].
Marketing Status Prescription
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D00822
MeSH ID D015283
PubChem ID 77995
TTD Drug ID D0Y5DO
NDC Product Code 13668-010; 71610-413; 63187-220; 58118-0023; 68645-569; 50090-3498; 50090-1298; 71335-0377; 70934-127; 70934-431; 68788-8962; 68071-4604; 65977-0018; 43063-481; 57664-509; 68071-2459; 65862-007; 0456-4021; 47621-022; 65862-005; 50090-3208; 51655-664; 65015-721; 71335-0480; 68071-2523; 50090-3136; 55700-838; 55154-3349; 61919-480; 59349-0010; 70934-842; 68645-570; 53002-1359; 13668-009; 61919-055; 68084-744; 53002-1579; 72657-111; 43063-670; 13668-011; 64220-105; 72657-110; 53002-2359; 68071-4123; 55700-851; 54838-540; 70518-0542; 68071-1906; 72761-006; 68788-0802; 70934-090; 68788-9692; 0615-8141; 55486-1572; 55111-902; 72789-071; 0904-6086; 0904-6085; 0456-4041; 61919-259; 65862-317; 31722-564; 43063-683; 70518-0070; 71335-0573; 60760-009; 0615-8022; 68645-559; 55111-343; 68645-571; 68071-3084; 42708-019; 0904-6084; 42708-091; 70518-1357; 65862-336; 51655-667; 68084-737; 65977-0053; 65372-1101; 70518-1917; 0615-8023; 17856-0564; 72657-109; 55154-3329; 55111-342; 65862-006; 63187-140; 68071-1830; 63629-8225; 63187-203; 53002-1360; 55700-787; 68071-2198; 50090-0892; 65862-074; 70934-304; 67296-1186; 53104-7738; 65372-1130; 51655-043; 71335-0238; 68071-5132; 55111-344; 68071-4324; 0456-4011; 53002-2360; 22365-112; 63187-679; 57664-507; 57664-508
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H22BrFN2O
CAS Registry Number 59729-32-7
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.Br
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abortion spontaneous18.01.04.001--Not Available
Accommodation disorder06.02.04.001--Not Available
Acne23.02.01.001--Not Available
Ageusia17.02.07.001; 07.14.03.003--Not Available
Aggression19.05.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Akathisia19.06.02.006; 17.01.02.002--
Alcohol intolerance14.02.01.001--
Alopecia23.02.02.001--
Amenorrhoea21.01.02.001; 05.05.01.002--
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Angle closure glaucoma06.03.01.001--Not Available
Anorgasmia19.08.01.001--
Anxiety19.06.02.002--
Apathy19.04.04.002--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Blood pressure diastolic13.14.03.021--Not Available
Blood pressure systolic13.14.03.012--Not Available
Bone pain15.02.01.001--
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