Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dextroamphetamine
Drug ID BADD_D00636
Description Dextroamphetamine is the dextrorotary enantiomer of amphetamine[A2505]. Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Indications and Usage Used to treat attention deficit hyperactivity disorder (ADHD).
Marketing Status Prescription; Discontinued
ATC Code N06BA02
DrugBank ID DB01576
KEGG ID D03740
MeSH ID D003913
PubChem ID 5826
TTD Drug ID D0T3LF
NDC Product Code 27808-085
Synonyms Dextroamphetamine | Dexamphetamine | Dexamfetamine | dextro-Amphetamine | dextro Amphetamine | d-Amphetamine | d Amphetamine | Dexedrine | DextroStat | Oxydess | Curban | Dextroamphetamine Sulfate | Sulfate, Dextroamphetamine | Dextro-Amphetamine Sulfate | Dextro Amphetamine Sulfate | d-Amphetamine Sulfate | d Amphetamine Sulfate
Chemical Information
Molecular Formula C9H13N
CAS Registry Number 51-64-9
SMILES CC(CC1=CC=CC=C1)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.001737%
Agitation19.06.02.001; 17.02.05.0120.006947%
Alopecia23.02.02.001--
Arthralgia15.01.02.0010.001737%
Blood pressure increased13.14.03.0050.001737%Not Available
Colitis ischaemic24.04.08.012; 07.08.01.0040.004342%Not Available
Confusional state19.13.01.001; 17.02.03.0050.003473%
Constipation07.02.02.001--
Death08.04.01.001--
Depressed level of consciousness17.02.04.0020.001737%
Depression19.15.01.0010.002605%
Diarrhoea07.02.01.001--
Disturbance in attention19.21.02.002; 17.03.03.0010.005210%
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.004342%
Drug abuse19.07.02.0100.000453%Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.0040.001737%Not Available
Dry eye06.08.02.0010.001737%
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyskinesia17.01.02.006--
Dysphoria19.04.02.004--Not Available
Erection increased21.03.01.004; 19.08.04.002--Not Available
Euphoric mood19.04.02.006--
Fatigue08.01.01.0020.002605%
Feeling abnormal08.01.09.0140.002605%Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Headache17.14.01.0010.004342%
Hepatotoxicity12.03.01.008; 09.01.07.0090.002605%Not Available
Hyperreflexia17.02.01.0020.001737%Not Available
Hypoaesthesia17.02.06.0230.002605%Not Available
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