Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute febrile neutrophilic dermatosis
ADR ID BADD_A00074
ADR Hierarchy
01      Blood and lymphatic system disorders
01.02      White blood cell disorders
01.02.01      Leukocytoses NEC
01.02.01.006      Acute febrile neutrophilic dermatosis
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.03      Dermal and epidermal conditions NEC
23.03.03.033      Acute febrile neutrophilic dermatosis
Description Condition characterized by large, rapidly extending, erythematous, tender plaques on the upper body usually accompanied by fever and dermal infiltration of neutrophilic leukocytes. It occurs mostly in middle-aged women, is often preceded by an upper respiratory infection, and clinically resembles ERYTHEMA MULTIFORME. Sweet syndrome is associated with LEUKEMIA. [MeSH]
MedDRA Code 10000748
MeSH ID D016463; D016463; D016463
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute febrile neutrophilic dermatosis | Sweet syndrome | Sweet's syndrome | Sweet Syndrome | Syndrome, Sweet | Dermatosis, Neutrophilic, Febrile, Acute | Gomm-Button Disease | Disease, Gomm-Button | Sweet's Syndrome | Sweets Syndrome | Syndrome, Sweet's | Gomm Button Disease | Disease, Gomm Button | Acute Febrile Neutrophilic Dermatosis | Neutrophilic Dermatosis, Acute Febrile
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00115Amiodarone0.001488%
BADD_D00129Amoxicillin0.000091%
BADD_D00142Anastrozole0.002640%
BADD_D00165Aripiprazole0.001335%
BADD_D00194Azacitidine0.003463%
BADD_D00195Azathioprine0.009334%
BADD_D00196Azathioprine sodium--
BADD_D00284Bortezomib--
BADD_D00306Budesonide0.000813%
BADD_D00356Carbamazepine0.001263%
BADD_D00560Cytarabine0.002398%
BADD_D00589Dasatinib0.000533%
BADD_D00593Decitabine--
BADD_D00623Dexamethasone0.000687%
BADD_D00653Diclofenac0.000119%
BADD_D00680Dimethyl fumarate0.001834%
BADD_D00897Filgrastim--
BADD_D00912Fluconazole0.000516%
BADD_D00941Flurbiprofen0.009698%
BADD_D00979Furosemide0.000158%
BADD_D00981Gabapentin0.000305%
BADD_D01081Hydralazine0.000828%
BADD_D01119Ibrutinib0.001332%
BADD_D01136Imatinib--
BADD_D01137Imatinib mesylate--
BADD_D01213Isotretinoin0.001263%
BADD_D01223Ixazomib--
BADD_D01230Ketoconazole0.000493%
BADD_D01253Lenalidomide--
BADD_D01257Letrozole0.003076%
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