Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Umbilical hernia
ADR ID BADD_A04414
ADR Hierarchy
07      Gastrointestinal disorders
07.16      Abdominal hernias and other abdominal wall conditions
07.16.03      Umbilical hernias
07.16.03.001      Umbilical hernia
Description A HERNIA due to an imperfect closure or weakness of the umbilical ring. It appears as a skin-covered protrusion at the UMBILICUS during crying, coughing, or straining. The hernia generally consists of OMENTUM or SMALL INTESTINE. The vast majority of umbilical hernias are congenital but can be acquired due to severe abdominal distention. | A congenital defect with major fissure in the ABDOMINAL WALL at the UMBILICUS resulting in the extrusion of VISCERA through the UMBILICUS. Unlike GASTROSCHISIS, omphalocele is covered with PERITONEUM but without overlying SKIN. [MeSH]
MedDRA Code 10045458
MeSH ID D006554
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Para-umbilical hernia | Umbilical hernia | Umbilical hernia NOS | Umbilical hernia without mention of obstruction or gangrene | Hernia, Umbilical | Exomphalos | Umbilical Hernia | Hernias, Umbilical | Umbilical Hernias | Omphalocele | Omphaloceles
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000808%
BADD_D00156Apremilast--
BADD_D00277Bisoprolol0.003354%
BADD_D00347Candesartan cilexetil0.003855%
BADD_D00497Clomiphene--
BADD_D00511Clozapine0.005605%
BADD_D00898Finasteride0.000962%
BADD_D01001Galsulfase--
BADD_D01005Ganirelix acetate--
BADD_D01242Lamivudine0.013914%
BADD_D01253Lenalidomide0.002895%
BADD_D01265Levetiracetam0.000952%
BADD_D01567Nilotinib0.001066%
BADD_D01617Ondansetron0.000200%
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01835Pregabalin0.000062%
BADD_D02029Sitagliptin0.000625%
BADD_D02047Sodium oxybate0.002422%
BADD_D02105Tacrolimus0.001419%
BADD_D02155Tenofovir disoproxil0.013329%
BADD_D02236Tofacitinib0.001158%
The 1th Page    1    Total 1 Pages