Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Neurotoxicity
ADR ID BADD_A03065
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.011      Neurotoxicity
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.10      Nervous system disorders NEC
17.02.10.002      Neurotoxicity
Description Not Available
MedDRA Code 10029350
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Neurotic toxicity | Neurotoxicity | Neurotoxicity NOS | CNS toxicity | Central nervous system toxicity
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
AcetylcholinesteraseP21836Not Available
Apoptosis regulator BAXG3V8T9Not Available
Apoptosis regulator Bcl-2P49950Not Available
Caspase-3P55213Not Available
Cytochrome c, somaticP62898Not Available
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
GABA receptor subunit B1M9TEZ7Not Available
Interferon gammaP01579T77664
Interleukin-1 alphaP01583T16340
Nitric oxide synthase, inducibleQ06518Not Available
Nuclear factor NF-kappa-B p105 subunitP19838T40192
Poly [ADP-ribose] polymerase 1P27008Not Available
Tumor necrosis factorP01375T20178
Tumor necrosis factorP16599Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000032-phenylbutyric acid--
BADD_D00088Altretamine--
BADD_D00103Amikacin--
BADD_D00115Amiodarone--
BADD_D00129Amoxicillin--
BADD_D00157Aprepitant--
BADD_D00209Baclofen--
BADD_D00282Blinatumomab--
BADD_D00284Bortezomib--
BADD_D00305Bromocriptine mesylate--
BADD_D00308Bupivacaine--
BADD_D00312Bupropion--
BADD_D00330Cabozantinib--
BADD_D00349Capecitabine--
BADD_D00364Carboplatin--
BADD_D00386Cefepime--
BADD_D00405Ceftriaxone--
BADD_D00474Cisplatin--
BADD_D00475Citalopram--
BADD_D00479Cladribine--
BADD_D00480Clarithromycin--
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine--
BADD_D00560Cytarabine--
BADD_D00561Cytarabine hydrochloride--
BADD_D00586Darunavir--
BADD_D00589Dasatinib--
BADD_D00623Dexamethasone--
BADD_D00633Dexrazoxane--
BADD_D00634Dexrazoxane hydrochloride--
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