Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01375Meloxicam sodium--
BADD_D01376Melphalan0.000974%
BADD_D01378Memantine0.003433%
BADD_D01379Memantine hydrochloride--
BADD_D01381Mepact--
BADD_D01386Mephenytoin--
BADD_D01389Mepolizumab--
BADD_D01391Mercaptoethanesulfonic acid--
BADD_D01392Mercaptopurine--
BADD_D01395Mersyndol--
BADD_D01397Mesalamine--
BADD_D01398Mesna--
BADD_D01401Metformin--
BADD_D01410Methazolamide--
BADD_D01414Methimazole--
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01424Methyl aminolevulinate hydrochloride--
BADD_D01431Methylphenidate--
BADD_D01432Methylphenidate hydrochloride--
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01439Methysergide--
BADD_D01442Metoclopramide--
BADD_D01443Metoclopramide hydrochloride--
BADD_D01444Metolazone0.000350%
BADD_D01445Metoprolol--
BADD_D01446Metoprolol succinate--
BADD_D01447Metoprolol tartrate--
BADD_D01448Metreleptin--
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ADReCS-Target
ADR Term Drug Name Target