Drug Name |
Metoclopramide hydrochloride |
Drug ID |
BADD_D01443 |
Description |
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system.[A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD). It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.[L8417]
One unique property of this drug is that it does not increase gastric acid secretion. It is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] |
Indications and Usage |
For the treatment of gastroesophageal reflux disease (GERD). It is also used in treating nausea and vomiting, and to increase gastric emptying. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
A03FA01 |
DrugBank ID |
DB01233
|
KEGG ID |
D02213
|
MeSH ID |
D008787
|
PubChem ID |
23659
|
TTD Drug ID |
D08VYV
|
NDC Product Code |
76045-213; 72089-307; 68071-4551; 0121-1576; 49452-4715; 0121-0576; 76045-101; 0404-9910; 55154-2353; 62559-166; 71872-7265; 55154-0450; 51552-1549; 51604-0005; 17856-0576; 68071-3262; 66689-031; 52584-414; 23155-240; 61919-150; 68788-6791; 40700-0010; 51927-5099; 43386-581; 43386-580; 51927-0185; 57451-1119; 57451-1139; 62559-165; 45562-1737; 76420-295 |
Synonyms |
Metoclopramide | 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide | Metaclopramide | Maxolon | Rimetin | Metoclopramide Hydrochloride | Hydrochloride, Metoclopramide | Metoclopramide Monohydrochloride | Monohydrochloride, Metoclopramide | Metoclopramide Monohydrochloride, Monohydrate | Primperan | Reglan | Cerucal | Metoclopramide Dihydrochloride | Dihydrochloride, Metoclopramide |