Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methazolamide
Drug ID BADD_D01410
Description A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Indications and Usage For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
Marketing Status Prescription; Discontinued
ATC Code S01EC05
DrugBank ID DB00703
KEGG ID D00655
MeSH ID D008704
PubChem ID 4100
TTD Drug ID D0C2II
NDC Product Code 42571-239; 0574-0790; 42571-240; 62559-240; 51407-026; 55806-021; 72969-047; 63629-1986; 50090-3233; 11712-530; 69575-4008; 63629-1958; 0574-0791; 62559-241; 48954-472; 68682-022; 11712-007; 71052-045; 68682-023; 51407-027; 63629-1987; 55806-020
Synonyms Methazolamide | N-Methylacetazolamide | N Methylacetazolamide
Chemical Information
Molecular Formula C5H8N4O3S2
CAS Registry Number 554-57-4
SMILES CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Aplastic anaemia01.03.03.002--Not Available
Asthenia08.01.01.001--Not Available
Body temperature increased13.15.01.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Crystalluria20.02.01.003--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Electrolyte imbalance14.05.01.002--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Glycosuria20.02.01.005--
Haematuria24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatic necrosis09.01.07.002--
Leukopenia01.02.02.001--Not Available
Malaise08.01.01.003--
Melaena24.07.02.013; 07.12.02.004--Not Available
Metabolic acidosis14.01.01.003--Not Available
Myopia06.02.04.002--Not Available
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
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