Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01270Levocabastine hydrochloride--
BADD_D01272Levocetirizine--
BADD_D01273Levocetirizine dihydrochloride--
BADD_D01274Levodopa-4'-monophosphate--
BADD_D01275Levofloxacin--
BADD_D01276Levoleucovorin--
BADD_D01281Levonorgestrel--
BADD_D01285Levothyroxine0.001964%
BADD_D01286Levothyroxine sodium--
BADD_D01291Linaclotide--
BADD_D01295Linezolid--
BADD_D01296Liothyronine0.005707%
BADD_D01298Liraglutide--
BADD_D01299Lisdexamfetamine dimesylate--
BADD_D01300Lisinopril--
BADD_D01301Lisuride--
BADD_D01302Lithium--
BADD_D01303Lithium carbonate--
BADD_D01304Lithium cation--
BADD_D01305Lithium hydroxide--
BADD_D01307Lodoxamide--
BADD_D01309Lomefloxacin--
BADD_D01310Lomefloxacin hydrochloride--
BADD_D01311Lomitapide0.001105%
BADD_D01312Lomitapide mesylate--
BADD_D01313Lomustine0.000907%
BADD_D01314Loperamide cation--
BADD_D01315Loperamide hydrochloride--
BADD_D01317Loratadine--
BADD_D01318Lorazepam--
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ADReCS-Target
ADR Term Drug Name Target