Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Encephalopathy
ADR ID BADD_A01462
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.001      Encephalopathy
Description A disorder characterized by a pathologic process involving the brain. [CTCAE] Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. [MeSH]
MedDRA Code 10014625
MeSH ID D001927
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Encephalopathy | Encephalopathy acute | Encephalopathy chronic | Encephalopathy NOS | Encephalopathy, unspecified | Influenza encephalopathy | Brain Diseases | Brain Disease | Brain Disorders | Brain Disorder | Intracranial CNS Disorders | Central Nervous System Intracranial Disorders | CNS Disorders, Intracranial | CNS Disorder, Intracranial | Intracranial CNS Disorder | Encephalon Diseases | Encephalon Disease | Intracranial Central Nervous System Disorders | Central Nervous System Disorders, Intracranial | Encephalopathies
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
Gamma-aminobutyric acid receptor subunit beta-1P15431Not Available
TransketolaseP29401T67754
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00016Acamprosate--
BADD_D00017Acamprosate calcium--
BADD_D00023Acetaminophen--
BADD_D00039Acyclovir--
BADD_D00040Acyclovir sodium--
BADD_D00052Albendazole--
BADD_D00062Aldesleukin--
BADD_D00066Alendronic acid--
BADD_D00076Allopurinol--
BADD_D00085Alprazolam--
BADD_D00100Ambrisentan--
BADD_D00105Amiloride hydrochloride--
BADD_D00114Aminosalicylic acid--
BADD_D00115Amiodarone--
BADD_D00129Amoxicillin--
BADD_D00132Amphotericin b--
BADD_D00151Apixaban--
BADD_D00165Aripiprazole--
BADD_D00167Armodafinil--
BADD_D00193Axitinib--
BADD_D00209Baclofen--
BADD_D00271Bicalutamide--
BADD_D00277Bisoprolol--
BADD_D00282Blinatumomab--
BADD_D00283Boceprevir--
BADD_D00284Bortezomib--
BADD_D00285Bosentan--
BADD_D00307Bumetanide--
BADD_D00312Bupropion--
BADD_D00318Busulfan--
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