Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Aortic dissection
ADR ID BADD_A00279
ADR Hierarchy
24      Vascular disorders
24.02      Aneurysms and artery dissections
24.02.03      Aortic aneurysms and dissections
24.02.03.002      Aortic dissection
Description An aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the tunica intima and TUNICA MEDIA causes luminal occlusion. Dissection at the media, or between the media and the outer ADVENTITIA causes aneurismal dilation. [MeSH]
MedDRA Code 10002895
MeSH ID D000784
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Aortic dissection | Dissecting aneurysm of aorta | Dissecting aortic aneurysm | Dissecting aortic aneurysm (any part) | Dissecting aortic aneurysm, abdominal | Dissecting aortic aneurysm, thoracic | Dissecting aortic aneurysm, thoracoabdominal | Dissecting aortic aneurysm, unspecified site | Ascending aortic dissection | Descending thoracic aortic dissection | Retrograde aortic dissection | Type B aortic dissection | Type A aortic dissection | Descending aortic dissection | Aneurysm, Dissecting | Dissecting Aneurysm | Aneurysms, Dissecting | Dissecting Aneurysms | Dissection, Blood Vessel | Blood Vessel Dissection | Aortic Dissection | Aortic Dissections | Dissection, Aortic | Dissections, Aortic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000834%
BADD_D00047Afatinib0.000112%
BADD_D00066Alendronic acid0.000044%
BADD_D00151Apixaban0.000347%
BADD_D00193Axitinib0.000392%
BADD_D00230Bendamustine--
BADD_D00330Cabozantinib0.000224%
BADD_D00374Carvedilol0.000021%
BADD_D00504Clopidogrel0.000086%
BADD_D00551Cyclosporine0.000166%
BADD_D00563Dabigatran0.009786%
BADD_D00564Dabigatran etexilate--
BADD_D00732Droxidopa0.000085%
BADD_D00775Enzalutamide0.000834%
BADD_D00858Everolimus0.000153%
BADD_D01119Ibrutinib0.000112%
BADD_D01222Ixabepilone--
BADD_D01254Lenvatinib0.000783%
BADD_D01318Lorazepam0.000031%
BADD_D01527Naltrexone--
BADD_D01567Nilotinib0.000112%
BADD_D01574Nitric oxide-
BADD_D01629Osimertinib0.000168%
BADD_D01687Pazopanib0.000224%
BADD_D01922Regorafenib0.000280%
BADD_D01954Rivaroxaban0.000475%
BADD_D02058Sorafenib0.000112%
BADD_D02098Sumatriptan0.000056%
BADD_D02100Sunitinib0.001287%
BADD_D02105Tacrolimus0.000297%
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