Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sumatriptan
Drug ID BADD_D02098
Description Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines.[A179761] Sumatriptan was granted FDA approval on 28 December 1992.[L6805]
Indications and Usage For the treatment of migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC01
DrugBank ID DB00669
KEGG ID D00451
MeSH ID D018170
PubChem ID 5358
TTD Drug ID D0Z6UC
NDC Product Code 69097-644; 58437-017; 0173-0478; 66993-084; 55700-918; 53873-057; 45802-598; 50090-2497; 0173-0524; 38779-2707; 70069-804; 62331-048; 42043-220; 0173-0736; 67857-809; 66993-083; 69452-344; 0527-1818; 42043-222; 58437-016; 63304-097; 42043-221; 0173-0739; 0480-2013; 53873-058; 0173-0737; 71921-170; 63187-164; 0143-9638; 63304-098; 63629-8701; 0173-0735; 66993-081; 55150-173; 69452-346; 52932-0733; 58437-018; 50370-0029; 53002-3562; 65145-118; 0527-1859; 45802-619; 67857-812; 0173-0479; 60429-995; 66993-082; 63187-323; 63304-099; 63629-8703; 50090-1605; 52482-013; 0173-0523; 67835-5011; 0480-2014; 69452-345; 53873-059; 0245-0812
Synonyms Sumatriptan | 3-(2-(Dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide | Sumatriptan Succinate | Succinate, Sumatriptan | GR-43175 | GR 43175 | GR43175 | Imigran
Chemical Information
Molecular Formula C14H21N3O2S
CAS Registry Number 103628-46-2
SMILES CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Cytogenetic abnormality5-hydroxytryptamine receptor 1FP30939T7865611167915; 11301495; 12789484
Cytogenetic abnormalityCalcitonin gene-related peptide 1P06881T9350911167915; 11301495; 12789484
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abortion18.01.01.001--Not Available
Accommodation disorder06.02.04.001--Not Available
Aggression19.05.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Akathisia19.06.02.006; 17.01.02.002--
Akinesia17.01.02.003--Not Available
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.0010.000257%
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Aortic aneurysm24.02.03.001--Not Available
Apathy19.04.04.002--Not Available
Aphasia19.21.01.001; 17.02.03.001--
Application site irritation12.07.01.003; 08.02.01.003--Not Available
Application site pain08.02.01.004; 12.07.01.004--Not Available
Application site pruritus08.02.01.005; 23.03.12.004; 12.07.01.005--Not Available
Application site warmth12.07.01.029; 08.02.01.029--Not Available
Arrhythmia02.03.02.001--Not Available
Arteriosclerosis24.04.02.001--Not Available
Arteriospasm coronary24.04.04.005; 02.02.02.005--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Asthenia08.01.01.0010.000644%Not Available
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