Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Infusion site reactions
ADR ID BADD_A06526
ADR Hierarchy
08      General disorders and administration site conditions
08.02      Administration site reactions
08.02.05      Infusion site reactions
12      Injury, poisoning and procedural complications
12.07      Administration site reactions
12.07.05      Infusion site reactions
Description Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA. [MeSH]
MedDRA Code 10068753
MeSH ID D000075662
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Injection Site Reaction | Injection Site Reactions | Injection Site Event | Injection Site Events | Injection Site Adverse Event | Infusion Site Reaction | Infusion Site Reactions | Infusion Site Adverse Reaction | Infusion Site Adverse Event
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug Name
BADD_D00023Acetaminophen
BADD_D00049Agalsidase beta
BADD_D00071Alglucosidase alfa
BADD_D00143Anidulafungin
BADD_D00157Aprepitant
BADD_D00158Aprotinin (bovine)
BADD_D00194Azacitidine
BADD_D00203Azithromycin
BADD_D00204Azithromycin dihydrate
BADD_D00225Belinostat
BADD_D00230Bendamustine
BADD_D00231Bendamustine hydrochloride
BADD_D00332Caffeine
BADD_D00349Capecitabine
BADD_D00376Caspofungin
BADD_D00377Caspofungin acetate
BADD_D00389Cefoperazone
BADD_D00398Ceftaroline fosamil
BADD_D00404Ceftobiprole
BADD_D00471Ciprofloxacin
BADD_D00479Cladribine
BADD_D00526Conivaptan
BADD_D00527Conivaptan hydrochloride
BADD_D00549Cyclophosphamide
BADD_D00559Cysteine hydrochloride
BADD_D00577Dantrolene sodium
BADD_D00581Daptomycin
BADD_D00609Deoxycholic acid
BADD_D00633Dexrazoxane
BADD_D00699Docetaxel
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