Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Premenstrual syndrome
ADR ID BADD_A03542
ADR Hierarchy
19      Psychiatric disorders
19.04      Mood disorders and disturbances NEC
19.04.02      Emotional and mood disturbances NEC
19.04.02.009      Premenstrual syndrome
21      Reproductive system and breast disorders
21.01      Menstrual cycle and uterine bleeding disorders
21.01.01      Menstruation and uterine bleeding NEC
21.01.01.007      Premenstrual syndrome
Description A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses. | A term used to describe the psychological aspects of PREMENSTRUAL SYNDROME, such as the "indescribable tension", depression, hostility, and increased seizure activity in women with seizure disorder. [MeSH]
MedDRA Code 10036618
MeSH ID D011293; D011293; D011293
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
PMS | PMT | Pre-menstrual tension syndrome | Premenstrual syndrome | Premenstrual tension | Premenstrual tension syndromes | Syndrome premenstrual | Premenstrual Syndrome | Premenstrual Syndromes | Syndrome, Premenstrual | Syndromes, Premenstrual | Premenstrual Tension | Premenstrual Tensions | Tension, Premenstrual | Tensions, Premenstrual
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam--
BADD_D00165Aripiprazole--
BADD_D00312Bupropion--
BADD_D00315Buserelin acetate--
BADD_D00349Capecitabine--
BADD_D00475Citalopram--
BADD_D00725Doxycycline--
BADD_D00727Doxycycline hyclate--
BADD_D00809Escitalopram0.000142%
BADD_D00820Esterified estrogens--
BADD_D00821Estradiol--
BADD_D00822Estradiol acetate--
BADD_D00824Estradiol hemihydrate--
BADD_D00844Ethinyl estradiol--
BADD_D00852Etonogestrel0.003712%
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D01150Indinavir--
BADD_D01162Insulin detemir--
BADD_D01213Isotretinoin0.001263%
BADD_D01277Levomefolate calcium--
BADD_D01281Levonorgestrel0.032310%
BADD_D01365Medroxyprogesterone--
BADD_D01366Medroxyprogesterone acetate0.000511%
BADD_D01586Norethindrone acetate--
BADD_D01590Nuvaring--
BADD_D01599Olanzapine--
BADD_D01852Progesterone--
BADD_D01966Ropinirole--
BADD_D02010Sertraline0.000060%
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