Drug Name |
Ethinyl estradiol |
Drug ID |
BADD_D00844 |
Description |
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.[A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.[A191107]
Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884] |
Indications and Usage |
For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
G03CA01; L02AA03 |
DrugBank ID |
DB00977
|
KEGG ID |
D00554
|
MeSH ID |
D004997
|
PubChem ID |
5991
|
TTD Drug ID |
D06NXY
|
NDC Product Code |
65089-0044; 12860-0463; 60870-0463; 63190-0620; 44132-002; 51927-1856; 22552-0034; 44132-010 |
Synonyms |
Ethinyl Estradiol | Estradiol, Ethinyl | Ethynyl Estradiol | Estradiol, Ethynyl | Ethinyloestradiol | 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)- | Ethinyl Estradiol Hemihydrate | Hemihydrate, Ethinyl Estradiol | Ethinyl Estradiol, (8 alpha)-Isomer | Ethinyl Estradiol, (8 alpha,17 alpha)-Isomer | Ethinyl Estradiol, (8 alpha,9 beta,13 alpha,14 beta)-Isomer | Progynon C | Microfollin | Microfollin Forte | Ethinyl-Oestradiol Effik | Ethinyl Oestradiol Effik | Ethinylestradiol Jenapharm | Jenapharm, Ethinylestradiol | Lynoral | Estinyl | Ethinyl Estradiol, (9 beta,17 alpha)-Isomer |