| Drug Name |
Norethindrone acetate |
| Drug ID |
BADD_D01586 |
| Description |
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.[A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol].[A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications including contraception and hormone replacement therapy.[L9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use as an oral contraceptive until 1962.[L10439] |
| Indications and Usage |
For the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
G03AC01; G03DC02 |
| DrugBank ID |
DB00717
|
| KEGG ID |
D00953
|
| MeSH ID |
D000077563
|
| PubChem ID |
5832
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
0378-7291; 68462-304; 50742-267; 72969-099; 64918-1404; 60870-0236; 0555-0211; 51285-424; 16571-658 |
| Synonyms |
Norethindrone Acetate | Norethisterone Acetate | Estr-4-en-3-one, 17-(acetyloxy)-17-ethynyl-, (17beta)- | Norethindrone Acetate, (17alpha)-(+-)-isomer | Aygestin | Norlutate | Norethindrone Acetate, (17alpha)-isomer |
