| Drug Name |
Olanzapine |
| Drug ID |
BADD_D01599 |
| Description |
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent.[A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions.[A177011] Olanzapine very closely resembles [clozapine] and only differs by two additional methyl groups and the absence of a chloride moiety.[T554] It was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] |
| Indications and Usage |
For the acute and maintenance treatment of schizophrenia and related psychotic disorders, as well as acute treatment of manic or mixed episodes of bipolar 1 disorder. Intramuscular olanzapine is indicated for the rapid control of agitated patients. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N05AH03 |
| DrugBank ID |
DB00334
|
| KEGG ID |
D00454
|
| MeSH ID |
D000077152
|
| PubChem ID |
135398745
|
| TTD Drug ID |
D0V4QS
|
| NDC Product Code |
33342-070; 60429-622; 13668-090; 50090-5102; 68084-740; 66529-0010; 0378-5512; 33342-067; 0002-4415; 63629-7514; 70771-1421; 14445-109; 0093-5246; 65862-563; 68084-528; 60429-625; 0002-4455; 63187-364; 71335-1363; 50268-617; 71210-4117; 35573-427; 43598-164; 63629-8719; 60429-623; 70518-1605; 59746-307; 0002-4112; 0002-4117; 71210-4112; 50090-3967; 70771-1419; 60505-3111; 55154-5896; 51293-847; 0110-4117; 51293-849; 70518-1115; 71335-0534; 65862-566; 65862-546; 33342-069; 13668-086; 64380-173; 60429-620; 63629-8718; 70518-1635; 35573-424; 0002-4420; 0002-4115; 60505-3114; 70518-2375; 50090-3933; 59746-308; 55150-308; 0110-4115; 49867-0056; 14799-2010; 0002-4456; 70518-3189; 51293-851; 62938-0030; 70771-1418; 60505-3113; 71335-0663; 70518-0110; 53104-7534; 0002-7597; 58118-0381; 71210-4115; 35573-423; 70518-0314; 60505-3140; 49884-323; 65862-658; 68382-369; 68084-525; 0002-4454; 65862-659; 65862-564; 0615-8244; 59746-306; 43598-166; 33342-085; 64380-172; 55111-168; 0781-9105; 14445-110; 68084-723; 55111-264; 35573-422; 62756-251; 0093-5247; 0093-5245; 67296-1722; 51293-852; 55154-6881; 14445-106; 0904-6377; 50090-3958; 60505-3278; 69543-382; 0615-8245; 71205-487; 35573-426; 0378-5513; 50090-5047; 0110-4415; 63187-340; 0378-5510; 51293-848; 69543-383; 70771-1416; 63187-429; 66993-683; 62938-0032; 63629-2237; 65862-562; 55154-6889; 60505-3112; 33342-068; 71335-1168; 60429-621; 70518-3054; 33342-083; 55700-862; 63419-0402; 65862-565; 51293-850; 0615-8243; 65862-657; 0615-8246; 70518-1535; 72643-023; 0378-5511; 55700-927; 55700-743; 33342-086; 69543-381; 0110-4420; 60505-3275; 70518-1582; 65862-656; 68788-7161; 51407-261; 13668-089; 33342-072; 62938-0033; 55111-263; 69543-384; 13668-088; 70518-2337; 63629-8274; 55111-167; 66993-685; 62938-0034; 64380-174; 55111-262; 71610-419; 58623-0069; 58032-0122; 35573-425; 0093-5248; 60429-624; 66993-682; 0002-4116; 65977-0026; 68084-529; 0904-6283; 65862-561; 53002-2505; 68382-367; 71335-1936; 71335-1760; 49884-321; 60505-3110; 68382-366; 70518-2698; 51407-264; 55111-265; 0517-0955; 0110-4116; 59746-309; 0110-4112; 70518-1501; 0904-6287; 68382-364; 68382-365; 15894-0006; 0904-6286; 70518-1611; 67184-0020; 63629-7902; 43598-165; 68382-368; 33342-071; 69543-380; 70518-2891; 49884-322; 51407-262; 63629-8717; 0002-4453; 71210-4420; 70518-2299; 65372-1183; 66993-684; 63629-8714; 60505-3276; 0781-3159; 60505-3277; 53002-1505; 55700-809; 69543-385; 64380-175; 71210-4116; 63187-844; 71335-0714; 66993-680; 71210-4415; 66993-681; 14445-111; 33342-084; 14445-108; 49587-103; 14445-107; 55111-163; 50268-616; 49884-320; 0904-6376; 70771-1417; 70518-2079; 51407-263; 63187-453; 70771-1420; 70518-0616; 64567-0017; 50268-615 |
| Synonyms |
Olanzapine | 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine | LY-170052 | LY 170052 | LY170052 | Zyprexa | Zolafren | LY 170053 | Olanzapine Pamoate |
