Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Esterified estrogens
Drug ID BADD_D00820
Description Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of menopause such as hot flashes, vaginal dryness, vaginal burning or irritation, or other hormonal changes in the vagina. It is being also for the prevention and treatment of osteoporosis.
Indications and Usage It is also indicated for the treatment of menopausal symptoms.
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB09381
KEGG ID Not Available
MeSH ID D042724
PubChem ID Not Available
TTD Drug ID Not Available
NDC Product Code 61570-072; 61570-073; 61570-075; 61570-074
Synonyms Estrogens, Esterified (USP) | Esterified Estrogens (USP)
Chemical Information
Molecular Formula Not Available
CAS Registry Number
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Alopecia23.02.02.001--
Amenorrhoea21.01.02.001; 05.05.01.002--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Arthralgia15.01.02.001--
Asthma22.03.01.002; 10.01.03.010--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Breast cancer21.05.01.003; 16.10.01.001--Not Available
Breast discharge21.05.05.001--Not Available
Breast enlargement21.05.04.001--Not Available
Carbohydrate tolerance decreased13.02.02.003--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chloasma23.05.01.001; 18.08.02.002--Not Available
Chorea17.01.01.001--Not Available
Corneal oedema06.04.02.001--Not Available
Dementia19.20.02.001; 17.03.01.001--Not Available
Depression19.15.01.001--
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Dysmenorrhoea21.01.01.002--
Ectropion of cervix21.06.01.004--Not Available
Endometrial cancer21.07.02.002; 16.12.02.001--Not Available
Endometrial hyperplasia21.07.01.002--Not Available
Epilepsy17.12.03.002--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Erythema nodosum23.07.02.001; 10.02.01.020--Not Available
Fibrocystic breast disease21.05.01.002; 16.14.01.003--Not Available
Galactorrhoea21.05.02.002; 05.03.04.002--Not Available
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