Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Maculopathy
ADR ID BADD_A02635
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.03      Retinal structural change, deposit and degeneration
06.09.03.007      Maculopathy
Description Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. [MeSH]
MedDRA Code 10025425
MeSH ID D008268
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Macula abnormality | Macula lutea abnormality | Macular cyst, hole, or pseudohole of retina | Maculopathy | Toxic maculopathy of retina | Macular dystrophy | Pigmentary maculopathy | Macular pigment atrophy | Bull's eye maculopathy | Macular Degeneration | Degeneration, Macular | Degenerations, Macular | Macular Degenerations | Age-Related Maculopathies | Age Related Maculopathies | Macular Degeneration, Age-Related | Macular Dystrophy | Dystrophies, Macular | Dystrophy, Macular | Macular Dystrophies | Maculopathies, Age-Related | Maculopathies, Age Related | Maculopathy, Age-Related | Maculopathy, Age Related | Age-Related Macular Degeneration | Age Related Macular Degeneration | Age-Related Macular Degenerations | Degeneration, Age-Related Macular | Degenerations, Age-Related Macular | Macular Degenerations, Age-Related | Age-Related Maculopathy | Age Related Maculopathy
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00142Anastrozole0.000754%
BADD_D00356Carbamazepine0.000842%
BADD_D00407Cefuroxime0.005428%
BADD_D00440Chloroquine0.000932%
BADD_D00504Clopidogrel0.000196%
BADD_D00511Clozapine0.014012%
BADD_D00560Cytarabine0.000533%
BADD_D00594Deferasirox0.008747%
BADD_D00596Deferoxamine0.014578%
BADD_D00699Docetaxel0.001598%
BADD_D00735Duloxetine hydrochloride--
BADD_D00924Fluocinolone acetonide--
BADD_D00981Gabapentin0.000102%
BADD_D01103Hydroxychloroquine0.002025%
BADD_D01418Methotrexate--
BADD_D01420Methoxsalen0.002057%
BADD_D01478Mitomycin0.002131%
BADD_D01479Mitotane--
BADD_D01511Nabumetone0.000737%
BADD_D01559Niacin0.000724%
BADD_D01567Nilotinib0.000533%
BADD_D01728Pentosan polysulfate0.017137%
BADD_D01834Prednisone0.000100%
BADD_D01912Ranibizumab--
BADD_D02010Sertraline0.001149%
BADD_D02247Topiramate0.003469%
BADD_D02271Triamcinolone0.001012%
BADD_D02464Fingolimod0.011580%
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