Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triamcinolone acetonide
Drug ID BADD_D02272
Description Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses.[L8249] Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.[L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.[L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients with macular edema associated with uveitis.[L38963]
Indications and Usage For the treatment of perennial and seasonal allergic rhinitis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A01AC01; C05AA12; D07AB09; D07XB02; H02AB08; R01AD11; R03BA06; S01BA05
DrugBank ID DB00620
KEGG ID D00983
MeSH ID D014222
PubChem ID 6436
TTD Drug ID Not Available
NDC Product Code 72189-277; 53002-9121; 0713-0676; 72603-108; 0065-0543; 49999-150; 62011-0320; 76420-162; 44118-711; 63629-8783; 68788-7814; 63187-214; 63629-8782; 70518-3373; 16714-150; 70121-1168; 41250-443; 68788-0149; 70121-1657; 68071-4168; 68071-2339; 41520-443; 63629-8708; 50090-1444; 33342-333; 68462-131; 68071-4397; 0713-0229; 59779-746; 22552-0032; 70121-1655; 70121-1651; 68071-2464; 16714-130; 70121-1652; 50090-2360; 68071-4630; 70518-1094; 67438-045; 0713-0225; 46439-8742; 71205-451; 71205-108; 63629-8778; 33342-331; 70518-0075; 12516-1510; 71565-040; 68071-4286; 52128-173; 0003-0293; 0703-0241; 0168-0003; 0168-0004; 51672-1284; 60432-560; 0703-0243; 68071-1623; 76420-085; 11822-0443; 0003-0494; 0703-0245; 63629-8456; 0168-0005; 49076-6701; 0713-0679; 49035-443; 68071-5070; 52565-011; 45802-045; 71205-124; 71161-135; 41167-5800; 63629-8785; 71205-627; 0316-0175; 71205-009; 66267-934; 35573-404; 70121-1049; 68788-7797; 45802-065; 53002-0150; 76420-220; 50090-4106; 68462-798; 71205-033; 76420-222; 45802-063; 51552-0033; 68071-4564; 24208-040; 21130-443; 12516-1509; 82298-123; 0713-0655; 45802-055; 71205-038; 41167-5900; 64380-871; 67877-317; 16714-140; 72189-039; 37808-443; 50090-2658; 52945-068; 50090-0819; 63187-025; 0003-0315; 50090-0295; 12516-1508; 50090-0162; 63629-8780; 0316-0165; 63629-8779; 0713-0228; 36800-621; 55910-280; 70518-2403; 33342-332; 74157-901; 68071-2516; 72603-202; 68071-2294; 11673-717; 63629-8781; 0363-0811; 60722-3012; 0316-0170; 64380-870; 45802-109; 0168-0002; 33342-328; 67877-251; 66267-933; 68788-7048; 51672-1335; 0168-0006; 70752-130; 0113-0443; 69842-244; 63187-495; 53002-9130; 59088-733; 61919-650; 63629-2407; 70121-1169; 68071-2362; 52565-010; 53002-9330; 63187-661; 45802-049; 67877-318; 46122-385; 76003-1145; 50090-3522; 72603-401; 10631-093; 0113-7005; 30142-443; 52565-056; 76420-203; 52817-811; 63629-8841; 68071-4391; 50090-2542; 68788-7501; 50090-0293; 68788-9172; 46287-010; 53002-0151; 70529-048; 63981-443; 50090-3802; 45802-064; 70121-1654; 33342-329; 45802-817; 50090-0256; 46439-8730; 45802-054; 63629-8707; 53002-9120; 33342-327; 63629-2406; 51927-0134; 64980-320; 70518-2393; 65089-0008; 68071-1803; 51672-1282; 49452-7900; 50090-0362; 52565-014; 0713-0226; 38779-0011; 70121-1653; 68788-7506; 68462-797; 57582-018; 51672-1267; 42571-385; 63187-870; 61919-594; 69256-443; 53002-9333; 59088-843; 50090-3754; 70000-0204; 53002-9334; 62991-1156; 70752-129; 46439-8703; 72288-443; 68071-2361; 70518-2285; 61919-619; 68071-1872; 30142-813; 70518-2938; 24470-922; 68071-4383; 52565-048; 45865-898; 60432-561; 49999-216; 53002-9331; 64980-429; 63275-9943; 70518-2963; 53002-9770; 64380-901; 41163-443; 40032-097; 51862-290; 0713-0766; 68071-4561; 63187-053
Synonyms Triamcinolone Acetonide | Acetonide, Triamcinolone | Cinonide | Tricort-40 | Tricort 40 | Tricort40 | Kenalog | Kenalog 40 | Azmacort | Kenacort A
Chemical Information
Molecular Formula C24H31FO6
CAS Registry Number 76-25-5
SMILES CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abnormal sensation in eye06.01.01.001--Not Available
Abscess11.01.08.001--Not Available
Abscess sterile08.01.05.008--Not Available
Acne23.02.01.001--Not Available
Adrenocortical insufficiency acute14.11.01.020; 05.01.02.005--Not Available
Alkalosis hypokalaemic14.01.02.002--Not Available
Alopecia23.02.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arachnoiditis17.06.01.001; 12.02.04.002--
Arrhythmia02.03.02.001--Not Available
Arthropathy15.01.01.003--Not Available
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrophy08.03.04.001--Not Available
Back pain15.03.04.005--
Benign intracranial hypertension17.07.02.001--Not Available
Bladder pain20.02.02.001--Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Blindness cortical17.17.01.017; 06.02.02.004--Not Available
Blister12.01.06.002; 23.03.01.001--Not Available
Blood cholesterol increased13.12.01.002--
Blood cortisol decreased13.10.09.004--Not Available
Blood potassium decreased13.11.01.010--Not Available
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