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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
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ADR Ontology
ADR Term
Gangrene
ADR ID
BADD_A01718
ADR Hierarchy
11
Infections and infestations
11.02
Bacterial infectious disorders
11.02.01
Bacterial infections NEC
11.02.01.003
Gangrene
23
Skin and subcutaneous tissue disorders
23.06
Skin vascular abnormalities
23.06.06
Skin ischaemic conditions
23.06.06.001
Gangrene
24
Vascular disorders
24.04
Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.05
Musculoskeletal necrosis and vascular insufficiency
24.04.05.003
Gangrene
Description
Death and putrefaction of tissue usually due to a loss of blood supply. [MeSH]
MedDRA Code
10017711
MeSH ID
D005734
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Gangrene | Gangrene cutaneous | Gangrene hemorrhagic | Gangrene NOS | Gangrene peripheral | Gangrene presenile | Gangrene skin | Gangrene spontaneous | Gangrene static | Gangrene symmetrical | Peripheral gangrene | Gangrene toe | Gangrene haemorrhagic | Wet gangrene | Gangrenes
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Not Available
Not Available
Not Available
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00062
Aldesleukin
-
-
BADD_D00151
Apixaban
-
-
BADD_D00161
Argatroban
-
-
BADD_D00164
Argipressin
-
-
BADD_D00285
Bosentan
0.002236%
BADD_D00344
Canagliflozin
0.030254%
BADD_D00410
Celecoxib
-
-
BADD_D00504
Clopidogrel
0.000245%
BADD_D00511
Clozapine
-
-
BADD_D00564
Dabigatran etexilate
0.004219%
BADD_D00578
Dapagliflozin
0.003015%
BADD_D00653
Diclofenac
0.000237%
BADD_D00708
Dopamine
0.000371%
BADD_D00709
Dopamine hydrochloride
-
-
BADD_D00765
Empagliflozin
0.008983%
BADD_D00782
Epinephrine
0.002123%
BADD_D00788
Epoprostenol
0.000371%
BADD_D00795
Ergonovine
-
-
BADD_D00796
Ergotamine
-
-
BADD_D00797
Ergotamine tartrate
-
-
BADD_D00858
Everolimus
0.000730%
BADD_D00871
Felbamate
-
-
BADD_D00974
Fragmin
-
-
BADD_D01009
Gemcitabine
-
-
BADD_D01010
Gemcitabine hydrochloride
-
-
BADD_D01059
Heparan sulfate
-
-
BADD_D01060
Heparin
0.050094%
BADD_D01110
Hydroxyurea
-
-
BADD_D01119
Ibrutinib
0.000533%
BADD_D01186
Ioversol
-
-
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