Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Gangrene
ADR ID BADD_A01718
ADR Hierarchy
11      Infections and infestations
11.02      Bacterial infectious disorders
11.02.01      Bacterial infections NEC
11.02.01.003      Gangrene
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.06      Skin ischaemic conditions
23.06.06.001      Gangrene
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.05      Musculoskeletal necrosis and vascular insufficiency
24.04.05.003      Gangrene
Description Death and putrefaction of tissue usually due to a loss of blood supply. [MeSH]
MedDRA Code 10017711
MeSH ID D005734
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Gangrene | Gangrene cutaneous | Gangrene hemorrhagic | Gangrene NOS | Gangrene peripheral | Gangrene presenile | Gangrene skin | Gangrene spontaneous | Gangrene static | Gangrene symmetrical | Peripheral gangrene | Gangrene toe | Gangrene haemorrhagic | Wet gangrene | Gangrenes
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00062Aldesleukin--
BADD_D00151Apixaban--
BADD_D00161Argatroban--
BADD_D00164Argipressin--
BADD_D00285Bosentan0.002236%
BADD_D00344Canagliflozin0.030254%
BADD_D00410Celecoxib--
BADD_D00504Clopidogrel0.000245%
BADD_D00511Clozapine--
BADD_D00564Dabigatran etexilate0.004219%
BADD_D00578Dapagliflozin0.003015%
BADD_D00653Diclofenac0.000237%
BADD_D00708Dopamine0.000371%
BADD_D00709Dopamine hydrochloride--
BADD_D00765Empagliflozin0.008983%
BADD_D00782Epinephrine0.002123%
BADD_D00788Epoprostenol0.000371%
BADD_D00795Ergonovine--
BADD_D00796Ergotamine--
BADD_D00797Ergotamine tartrate--
BADD_D00858Everolimus0.000730%
BADD_D00871Felbamate--
BADD_D00974Fragmin--
BADD_D01009Gemcitabine--
BADD_D01010Gemcitabine hydrochloride--
BADD_D01059Heparan sulfate--
BADD_D01060Heparin0.050094%
BADD_D01110Hydroxyurea--
BADD_D01119Ibrutinib0.000533%
BADD_D01186Ioversol--
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