Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meperidine
Drug ID BADD_D01384
Description A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Indications and Usage Used to control moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AB02
DrugBank ID DB00454
KEGG ID D08343
MeSH ID D008614
PubChem ID 4058
TTD Drug ID D00UYE
NDC Product Code Not Available
Synonyms Meperidine | Pethidine | Isonipecain | Dolsin | Dolosal | Dolin | Operidine EPJ-I | Operidine EPJ I | Dolantin | Dolargan | Meperidine Hydrochloride | Lidol | Lydol | Demerol | Dolcontral
Chemical Information
Molecular Formula C15H21NO2
CAS Registry Number 57-42-1
SMILES CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Agitation19.06.02.001; 17.02.05.0120.010415%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.034717%
Anaphylactic shock10.01.07.002; 24.06.02.0040.003472%Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anuria20.01.03.002--Not Available
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Bradycardia02.03.02.002--Not Available
Burning sensation17.02.06.001; 08.01.09.0290.005208%Not Available
Cardiac arrest02.03.04.001--
Cold sweat23.02.03.002; 08.01.03.024--Not Available
Coma17.02.09.001--Not Available
Complex partial seizures17.12.02.003--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Delirium19.13.02.001--
Depressed level of consciousness17.02.04.002--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug abuse19.07.02.010--Not Available
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.0150.003472%Not Available
Drug hypersensitivity10.01.01.0011.097049%Not Available
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dysphoria19.04.02.004--Not Available
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