Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ergonovine
Drug ID BADD_D00795
Description An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Indications and Usage Used to treat postpartum haemorrhage and postabortion haemorrhage in patients with uterine atony.
Marketing Status Not Available
ATC Code G02AB03
DrugBank ID DB01253
KEGG ID D07905
MeSH ID D004874
PubChem ID 443884
TTD Drug ID D0C1IW
NDC Product Code Not Available
Synonyms Ergonovine | Ergometrin | Ergobasin | Ergometrine | Ergonovine Maleate | Ergometrine Maleate | Ergotrate
Chemical Information
Molecular Formula C19H23N3O2
CAS Registry Number 60-79-7
SMILES CC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
HyperphosphatasaemiaIntercellular adhesion molecule 1P05362T262039176229; 10762620; 9397994; 11431739; 11110625; 8690410; 11182296
Liver injuryIntercellular adhesion molecule 1P05362T262039176229; 10762620; 9397994; 11431739; 11110625; 8690410; 11182296
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Arteriospasm coronary24.04.04.005; 02.02.02.005--Not Available
Bradycardia02.03.02.002--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug interaction08.06.03.001--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Gangrene11.02.01.003; 24.04.05.003; 23.06.06.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematuria24.07.01.047; 20.02.01.006--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Intestinal infarction24.04.08.008; 07.15.02.006--Not Available
Intestinal ischaemia24.04.08.001; 07.15.02.001--Not Available
Muscle spasms15.05.03.004--
Myasthenia gravis15.05.08.001; 10.04.05.001; 17.05.04.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Oesophageal spasm07.02.04.004--Not Available
Palpitations02.01.02.003--
Pleural fibrosis22.05.03.003--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Shock24.06.02.002--Not Available
Thrombophlebitis24.01.02.001--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
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