Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02175Tetrabenazine--
BADD_D02183Tetraethylenepentamine--
BADD_D02187Tetrakis(1-isocyano-2-methoxy-2-methyl-propane)-copper(i) tetrafluoroborate--
BADD_D02188Tetrakis(2-methoxyisobutylisocyanide)copper(i) tetrafluoroborate--
BADD_D02192Thalidomide0.038313%
BADD_D02196Thiabendazole--
BADD_D02203Thiotepa--
BADD_D02204Thiothixene--
BADD_D02208Thyrotropin alfa--
BADD_D02210Tiagabine--
BADD_D02212Tiaprofenic acid--
BADD_D02214Ticagrelor--
BADD_D02218Tiludronate disodium--
BADD_D02219Timolol0.000341%
BADD_D02220Timolol maleate--
BADD_D02221Tinidazole--
BADD_D02223Tiopronin0.000616%
BADD_D02226Tipranavir--
BADD_D02227Tipranavir disodium--
BADD_D02230Tizanidine--
BADD_D02231Tizanidine hydrochloride--
BADD_D02236Tofacitinib0.767461%
BADD_D02237Tofacitinib citrate--
BADD_D02238Tolazamide--
BADD_D02241Tolcapone--
BADD_D02244Tolterodine--
BADD_D02245Tolterodine tartrate--
BADD_D02246Tolvaptan--
BADD_D02247Topiramate--
BADD_D02248Topotecan0.003156%
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ADReCS-Target
ADR Term Drug Name Target