Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Tolterodine
Drug ID BADD_D02244
Description Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Indications and Usage For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
Marketing Status approved; investigational
ATC Code G04BD07
DrugBank ID DB01036
KEGG ID D00646
MeSH ID D000068737
PubChem ID 443879
TTD Drug ID D0BZ7W
NDC Product Code 13668-189; 13668-190; 0904-6592; 60687-330; 0904-6593; 65427-022; 60687-319
UNII WHE7A56U7K
Synonyms Tolterodine Tartrate | Tartrate, Tolterodine | Tolterodine | Detrol | Detrol LA | Urotrol | PHA-686464B | PHA 686464B | PHA686464B | Detrusitol | Unidet
Chemical Information
Molecular Formula C22H31NO
CAS Registry Number 124937-51-5
SMILES CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.0030.000498%
Abdominal rigidity07.01.05.011--Not Available
Accommodation disorder06.02.04.001--Not Available
Amnesia17.03.02.001; 19.20.01.0010.000882%
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.0010.000339%
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Atrial flutter02.03.03.0030.000226%
Back pain15.03.04.0050.001379%
Bladder pain20.02.02.001--Not Available
Blister23.03.01.001; 12.01.06.0020.000226%Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Cataract06.06.01.001--
Chest pain08.01.08.002; 02.02.02.011; 22.12.02.0030.000769%Not Available
Condition aggravated08.01.03.0040.002035%Not Available
Confusional state19.13.01.001; 17.02.03.0050.001832%
Constipation07.02.02.0010.000882%
Deafness04.02.01.0010.000452%Not Available
Death08.04.01.001--
Decubitus ulcer23.03.11.0060.000226%Not Available
Dehydration14.05.05.0010.000769%
Delusion19.10.01.001--
Dementia19.20.02.001; 17.03.01.0010.000226%Not Available
Diabetes mellitus14.06.01.001; 05.06.01.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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