Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Thiabendazole
Drug ID BADD_D02196
Description 2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Indications and Usage For the treatment of strongyloidiasis (threadworm), cutaneous larva migrans (creeping eruption), visceral larva migrans, and trichinosis.
Marketing Status Discontinued
ATC Code D01AC06; P02CA02
DrugBank ID DB00730
KEGG ID D00372
MeSH ID D013827
PubChem ID 5430
TTD Drug ID D08QCJ
NDC Product Code 59014-0050; 49452-7723; 68022-7046; 51927-2278
Synonyms Thiabendazole | Tiabendazol | Thibendole | 2-(4'-Thiazolyl)Benzimidazole | Mintezol | Omnizole | Mintesol
Chemical Information
Molecular Formula C10H7N3S
CAS Registry Number 148-79-8
SMILES C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal sensation in eye06.01.01.001--Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema10.01.05.009; 23.04.01.001--Not Available
Anorectal disorder07.03.01.001--Not Available
Ascariasis11.08.01.001; 07.19.02.004--Not Available
Asthenia08.01.01.001--Not Available
Chills15.05.03.016; 08.01.09.001--
Cholestasis09.01.01.001--Not Available
Circulatory collapse24.06.02.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Coordination abnormal17.02.02.004--Not Available
Crystalluria20.02.01.003--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Enuresis20.02.02.003; 19.07.04.001--Not Available
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal pain07.01.05.005--
Haematuria24.07.01.047; 20.02.01.006--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatocellular injury09.01.07.008--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
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