Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tolterodine tartrate
Drug ID BADD_D02245
Description Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Indications and Usage For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
Marketing Status Prescription; Discontinued
ATC Code G04BD07
DrugBank ID DB01036
KEGG ID D01148
MeSH ID D000068737
PubChem ID 9847786
TTD Drug ID D0BZ7W
NDC Product Code 31722-608; 10135-707; 53104-7572; 65862-394; 0093-7164; 52286-0018; 73152-026; 31722-805; 53747-035; 70436-160; 64552-4002; 59762-0048; 50370-0023; 0009-5190; 11014-0374; 29300-240; 65977-0029; 11014-0122; 43975-322; 49706-1835; 43975-323; 33342-098; 59762-0800; 10135-706; 0009-0420; 55289-132; 0093-7163; 11014-0123; 59762-0047; 0093-0018; 70518-2794; 16571-126; 0009-4544; 50090-3475; 55111-855; 70436-161; 14593-901; 71205-319; 59762-0170; 27241-191; 33342-097; 70518-1416; 31722-806; 31722-607; 27241-192; 71666-009; 16571-127; 0009-4541; 0093-0010; 29300-239; 65427-020; 0009-5191
Synonyms Tolterodine Tartrate | Tartrate, Tolterodine | Tolterodine | Detrol | Detrol LA | Urotrol | PHA-686464B | PHA 686464B | PHA686464B | Detrusitol | Unidet
Chemical Information
Molecular Formula C26H37NO7
CAS Registry Number 124937-52-6
SMILES CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Accommodation disorder06.02.04.001--Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Delusion19.10.01.001--
Dementia19.20.02.001; 17.03.01.001--Not Available
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry eye06.08.02.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal pain07.01.05.005--
Hallucination19.10.02.002--
Headache17.14.01.001--
Infection11.01.08.002--Not Available
Influenza like illness08.01.03.010--
Memory impairment17.03.02.003; 19.20.01.003--
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