Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Diplegia
ADR ID BADD_A01274
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.04      Paralysis and paresis (excl cranial nerve)
17.01.04.015      Diplegia
Description A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7) [MeSH]
MedDRA Code 10013033
MeSH ID D002547
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Diplegia | Diplegia of upper limbs | Paralysis legs | Diplegia of lower limbs | Spastic diplegia | Paralysis of arms | Cerebral Palsy | CP (Cerebral Palsy) | Cerebral Palsy, Dystonic-Rigid | Cerebral Palsies, Dystonic-Rigid | Cerebral Palsy, Dystonic Rigid | Dystonic-Rigid Cerebral Palsies | Dystonic-Rigid Cerebral Palsy | Cerebral Palsy, Mixed | Mixed Cerebral Palsies | Mixed Cerebral Palsy | Cerebral Palsy, Monoplegic, Infantile | Monoplegic Infantile Cerebral Palsy | Infantile Cerebral Palsy, Monoplegic | Cerebral Palsy, Quadriplegic, Infantile | Quadriplegic Infantile Cerebral Palsy | Infantile Cerebral Palsy, Quadriplegic | Cerebral Palsy, Rolandic Type | Rolandic Type Cerebral Palsy | Cerebral Palsy, Congenital | Congenital Cerebral Palsy | Little Disease | Little's Disease | Spastic Diplegia | Diplegias, Spastic | Spastic Diplegias | Diplegia, Spastic | Monoplegic Cerebral Palsy | Cerebral Palsies, Monoplegic | Cerebral Palsy, Monoplegic | Monoplegic Cerebral Palsies | Cerebral Palsy, Athetoid | Athetoid Cerebral Palsy | Cerebral Palsies, Athetoid | Cerebral Palsy, Dyskinetic | Cerebral Palsies, Dyskinetic | Dyskinetic Cerebral Palsy | Cerebral Palsy, Atonic | Atonic Cerebral Palsy | Cerebral Palsy, Hypotonic | Hypotonic Cerebral Palsies | Hypotonic Cerebral Palsy | Cerebral Palsy, Diplegic, Infantile | Diplegic Infantile Cerebral Palsy | Infantile Cerebral Palsy, Diplegic | Cerebral Palsy, Spastic | Spastic Cerebral Palsies | Spastic Cerebral Palsy
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00209Baclofen0.000505%
BADD_D00260Betamethasone--
BADD_D00308Bupivacaine--
BADD_D00504Clopidogrel0.000098%
BADD_D00561Cytarabine hydrochloride--
BADD_D00974Fragmin--
BADD_D00981Gabapentin0.000127%
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01086Hydrocortisone--
BADD_D01186Ioversol--
BADD_D01253Lenalidomide0.001737%
BADD_D01269Levobupivacaine--
BADD_D01418Methotrexate--
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01435Methylprednisolone hemisuccinate--
BADD_D01633Oxaliplatin0.000799%
BADD_D01804Posaconazole--
BADD_D01831Prednisolone--
BADD_D01832Prednisolone acetate--
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.000590%
BADD_D01954Rivaroxaban0.001071%
BADD_D02010Sertraline0.000121%
BADD_D02026Simvastatin0.000046%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02105Tacrolimus0.001419%
BADD_D02115Tapentadol0.002920%
The 1th Page    1 2    Next   Last    Total 2 Pages