Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.001300%Not Available
Abdominal distension07.01.04.0010.000557%
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.0030.000975%
Abnormal dreams17.15.02.001; Available
Abscess11.01.08.0010.000093%Not Available
Accidental overdose12.06.03.002--Not Available
Acne23.02.01.001--Not Available
Activated partial thromboplastin time prolonged13.01.02.0010.000093%
Acute abdomen07.01.06.0150.000093%Not Available
Acute pulmonary oedema22.01.03.005; Available
Acute respiratory distress syndrome22.01.03.0010.000097%
Acute respiratory failure22.02.06.001; Available
Addison's disease14.11.01.025;; Available
Adrenal insufficiency14.11.01.004;
Aggression19.05.01.001--Not Available
Alanine aminotransferase increased13.03.01.003--
Alcohol abuse19.07.02.007--Not Available
Alcoholism19.07.02.001--Not Available
Altered state of consciousness19.07.01.003; Available
Amblyopia06.02.01.001--Not Available
Anaesthetic complication pulmonary22.02.07.005; Available
Anaphylactic reaction24.06.03.006;
Anaphylactic shock24.06.02.004; Available
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