| ADR Ontology |
| ADR Term |
Toxicity to various agents |
| ADR ID |
BADD_A06627 |
| ADR Hierarchy |
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| Description |
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. [MeSH] |
| MedDRA Code |
10070863 |
| MeSH ID |
D064420
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Anti-infective agent toxicity | Barbiturate intoxication | Barbiturate intoxication (NOS) | Bromide intoxication | Brominism | Bromism | Digitalis intoxication | Digitalis intoxication (NOS) | Digitalis toxicity | Digoxin effect | Digoxin toxicity | Drug intoxication | Drug reactions and intoxications specific to newborn | Drug toxicity | Drug toxicity (NOS) | Drug toxicity NOS | Immunosuppressant intoxication | Iodide intoxication | Iodism | Iodism symptom | Late effect of poisoning due to drug, medicament or biological substance | Late effect of poisoning due to drug, medicinal or biological substance | Lithium poisoning | Opiate toxicity | Pathological drug intoxication | Poisoning by acidifying agents | Poisoning by adrenal cortical steroids | Poisoning by agents primarily acting on the smooth and skeletal muscle and respiratory system | Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system | Poisoning by agents primarily affecting blood constituents | Poisoning by agents primarily affecting skin and mucous memb, ophth, oto/rhin/lary, and den drugs | Poisoning by agents primarily affecting the cardiovascular system | Poisoning by agents primarily affecting the CVS | Poisoning by agents primarily affecting the gastrointestinal system | Poisoning by agents primarily affecting the gut | Poisoning by alcohol deterrents | Poisoning by alkalizing agents | Poisoning by analeptics | Poisoning by analgesics, antipyretics, and antirheumatic drugs | Poisoning by analgesics, antipyretics, and antirheumatics | Poisoning by androgens and anabolic congeners | Poisoning by antacids and antigastric secretion drugs | Poisoning by anterior pituitary hormones | Poisoning by anthelminthics | Poisoning by anthelmintics | Poisoning by anti-common cold drugs | Poisoning by anti-common-cold drugs | Poisoning by anti-infectives and other drugs and preparations for ear, nose, and throat | Poisoning by anti-Parkinsonism drugs | Poisoning by antiallergic and antiemetic drugs | Poisoning by antiasthmatics | Poisoning by antibiotic drugs | Poisoning by antibiotics | Poisoning by anticoagulant antagonists and other coagulants | Poisoning by anticoagulants | Poisoning by anticonvulsants and anti-Parkinsonism drugs | Poisoning by antidepressants | Poisoning by antidiarrheal drugs | Poisoning by antidiarrhoeal drugs | Poisoning by antidotes and chelating agents, not elsewhere classified | Poisoning by antifungal antibiotics | Poisoning by antilipemic and antiarteriosclerotic drugs | Poisoning by antimalarials and drugs acting on other blood protozoa | Poisoning by antineoplastic and immunosuppressive drugs | Poisoning by antineoplastic antibiotics | Poisoning by antipruritics | Poisoning by antirheumatics (antiphlogistics) | Poisoning by antithyroid agents | Poisoning by antitussives | Poisoning by antivaricose drugs, including sclerosing agents | Poisoning by antiviral drugs | Poisoning by aromatic analgesics, not elsewhere classified | Poisoning by arsenical anti-infectives | Poisoning by bacterial vaccines | Poisoning by barbiturates | Poisoning by BCG vaccine | Poisoning by benzodiazepine-based tranquilizers | Poisoning by benzodiazepine-based tranquillizers | Poisoning by bromine compounds | Poisoning by butyrophenone-based tranquilizers | Poisoning by butyrophenone-based tranquillizers | Poisoning by capillary-active drugs | Poisoning by carbonic acid anhydrase inhibitors | Poisoning by cardiac rhythm regulators | Poisoning by cardiotonic glycosides and drugs of similar action | Poisoning by central nervous system muscle-tone depressants | Poisoning by central nervous system stimulants | Poisoning by chloral hydrate group | Poisoning by chloramphenicol group | Poisoning by cholera vaccine | Poisoning by coronary vasodilators | Poisoning by dental drugs topically applied | Poisoning by dietetics | Poisoning by digestants | Poisoning by diphtheria vaccine | Poisoning by drugs primarily affecting the ANS |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | Q9NQ66 | T26846 | | Catechol O-methyltransferase | P21964 | T76904 | | Cytochrome P450 2C9 | P11712 | T19244 | | Cytochrome P450 2D6 | P10635 | T57392 | | Cytochrome P450 2E1 | P05181 | Not Available | | Cytochrome P450 3A4 | P08684 | T37848 | | Dihydropyrimidine dehydrogenase [NADP(+)] | Q12882 | T75890 | | Epoxide hydrolase 1 | P07099 | Not Available | | HLA class I histocompatibility antigen, B alpha chain | P01889 | Not Available | | HLA class II histocompatibility antigen, DR beta 5 chain | Q30154 | Not Available | | HLA class II histocompatibility antigen, DRB1 beta chain | P01911 | Not Available | | HLA-DR3 | Q29887 | Not Available | | Phospholipase A2 | P04054 | T31479 | | Thymidine kinase, cytosolic | P04183 | T30081 |
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| Drugs Leading to the ADR |
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