| Pharmaceutical Information |
| Drug Name |
Glucagon |
| Drug ID |
BADD_D01025 |
| Description |
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643]
Glucagon was granted FDA approval on 14 November 1960.[L7631] |
| Indications and Usage |
For treatment of severe hypoglycemia, also used in gastrointestinal imaging |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
H04AA01 |
| DrugBank ID |
DB00040
|
| KEGG ID |
D00116
|
| MeSH ID |
D005934
|
| PubChem ID |
16132283
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
63323-596; 63083-1555; 41524-0005; 55463-0009; 0002-8031; 0002-6145; 0002-7529; 43742-0734; 0548-5850; 63323-594; 63323-593; 51662-1498; 63323-582 |
| Synonyms |
Glucagon | Proglucagon (33-61) | HG-Factor | HG Factor | Glukagon | Glucagon (1-29) | Hyperglycemic-Glycogenolytic Factor | Hyperglycemic Glycogenolytic Factor |
|
| Chemical Information |
| Molecular Formula |
C153H225N43O49S |
| CAS Registry Number |
9007-92-5 |
| SMILES |
CC(C)CC(C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC
=C21)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC(=O)O)NC(=O)C
(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(
=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC5
=CC=C(C=C5)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC6=CC=CC=C6)NC(=O
)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CC7=CN=CN7)N |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
