Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status Prescription; Discontinued
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 70518-3218; 60429-016; 72322-1049; 68084-918; 0904-6785; 60505-2965; 68254-5001; 68254-5002; 0078-0385; 70748-218; 70518-3255; 68084-907; 0904-6786; 24979-160; 50268-559; 51187-0004; 0378-4201; 60505-2966; 67877-426; 52076-6215; 0378-4202; 16729-261; 67877-427; 16729-189; 72322-1048; 70436-172; 60429-017; 24979-161; 20076-0405; 0078-0386; 70436-173; 57885-0009; 65727-011; 70748-217
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.005211%Not Available
Abdominal distension07.01.04.0010.001158%
Abdominal pain07.01.05.0020.005790%
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Abdominal tenderness07.01.05.004--Not Available
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Abscess11.01.08.001--Not Available
Acidosis14.01.03.002--
Acne23.02.01.001--Not Available
Acquired immunodeficiency syndrome11.05.17.007; 10.03.03.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.0010.004053%Not Available
Akathisia19.06.02.006; 17.01.02.002--
Alanine aminotransferase increased13.03.01.003--
Albuminuria20.02.01.001--Not Available
Alkalosis14.01.02.001--
Alopecia23.02.02.001--
Amblyopia06.02.01.001--Not Available
Amnesia19.20.01.001; 17.03.02.0010.001158%
Anaemia01.03.02.0010.005211%
Anaphylactic reaction10.01.07.001; 24.06.03.0060.001158%
Anaphylactic shock24.06.02.004; 10.01.07.0020.001158%Not Available
Angina pectoris24.04.04.002; 02.02.02.0020.001158%
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anhidrosis23.02.03.001--Not Available
Anorectal disorder07.03.01.001--Not Available
Anxiety19.06.02.002--
Apathy19.04.04.002--Not Available
Aphthous ulcer07.05.06.0020.001737%Not Available
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