Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Muscle tightness
ADR ID BADD_A04877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.007      Muscle tightness
Description The state of activity or tension of a muscle beyond that related to its physical properties, that is, its active resistance to stretch. In skeletal muscle, tonus is dependent upon efferent innervation. (Stedman, 25th ed) [MeSH]
MedDRA Code 10049816
MeSH ID D009129
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Neck tightness | Perioral tension | Tightness in jaw | Tightness of jaw muscles | Muscle tightness | Tightness of back muscles | Muscle tension | Muscle Tonus | Tonus, Muscle | Muscle Tightness | Tightness, Muscle | Muscular Tension | Tension, Muscular | Muscle Tension | Tension, Muscle
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00648Diazepam0.000136%
BADD_D00652Dichlorphenamide0.000588%
BADD_D00653Diclofenac0.000051%
BADD_D00680Dimethyl fumarate0.015003%
BADD_D00686Diphenhydramine0.000134%
BADD_D00692Dipyridamole--
BADD_D00732Droxidopa0.000761%
BADD_D00734Duloxetine0.000093%
BADD_D00735Duloxetine hydrochloride--
BADD_D00782Epinephrine--
BADD_D00788Epoprostenol0.000082%
BADD_D00809Escitalopram0.000019%
BADD_D00821Estradiol0.000068%
BADD_D00854Etoposide--
BADD_D00870Febuxostat--
BADD_D00898Finasteride0.000211%
BADD_D00931Fluorouracil0.000184%
BADD_D00932Fluoxetine0.000096%
BADD_D00976Frovatriptan--
BADD_D00981Gabapentin--
BADD_D00984Gadobutrol0.041969%
BADD_D00987Gadofosveset--
BADD_D01054Haloperidol--
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01120Ibuprofen--
BADD_D01136Imatinib0.000437%
BADD_D01149Indapamide0.000377%
BADD_D01178Iodixanol0.007113%
BADD_D01180Iohexol0.014227%
BADD_D01182Iopromide0.007113%
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