Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan
Drug ID BADD_D00976
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status Prescription
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D07997
MeSH ID C108128
PubChem ID 77992
TTD Drug ID D06FPQ
NDC Product Code 0378-3140
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C14H17N3O
CAS Registry Number 158747-02-5
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Amnesia19.20.01.001; 17.03.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arteriospasm coronary24.04.04.005; 02.02.02.005--Not Available
Arthralgia15.01.02.001--
Arthropathy15.01.01.003--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Back pain15.03.04.005--
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Bone pain15.02.01.001--
Bradycardia02.03.02.002--Not Available
Cardiovascular disorder24.03.02.009; 02.01.01.001--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Change of bowel habit07.02.03.002--Not Available
Cheilitis23.03.03.025; 07.05.01.001--
Chest discomfort08.01.08.019; 22.02.08.001; 02.02.02.009--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Chills15.05.03.016; 08.01.09.001--
Coagulopathy01.01.02.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Dehydration14.05.05.001--
Depression19.15.01.001--
Dermatitis bullous23.03.01.002--
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