| Drug Name |
Ibuprofen |
| Drug ID |
BADD_D01120 |
| Description |
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.[A39075] Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID.[A39076]
On the available products, ibuprofen is administered as a racemic mixture. Once administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase. In particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.[A39194] |
| Indications and Usage |
Not Available |
| Marketing Status |
Prescription; OTC; Discontinued |
| ATC Code |
C01EB16; G02CC01; M01AE01; M02AA13; R02AX02 |
| DrugBank ID |
DB01050
|
| KEGG ID |
D00126
|
| MeSH ID |
D007052
|
| PubChem ID |
3672
|
| TTD Drug ID |
D0R1QE
|
| NDC Product Code |
41520-604; 62207-357; 62011-0010; 73408-509; 42291-442; 69256-057; 0363-1461; 59651-072; 50804-750; 41226-600; 56062-131; 72476-112; 49483-114; 55319-396; 50090-4333; 25000-122; 21130-035; 50090-4367; 47682-714; 11822-0897; 63868-805; 21130-911; 0573-0169; 71335-1503; 49035-749; 50090-3978; 50580-933; 30142-745; 0904-6747; 71610-456; 42681-7077; 36800-348; 50090-5223; 0363-0392; 11673-349; 71921-181; 70518-3313; 72288-604; 66267-963; 71335-0223; 72189-170; 55758-304; 50844-268; 53002-5710; 11822-3061; 68210-8100; 71335-1008; 56062-897; 72288-763; 71679-111; 11673-991; 49035-745; 59651-075; 71205-464; 64024-003; 65162-356; 11673-593; 38779-0299; 71862-003; 80267-604; 58624-0050; 55910-046; 41250-419; 71610-387; 53002-3370; 0472-1761; 53002-3372; 11673-749; 50090-2549; 69842-851; 68788-7745; 61919-628; 59556-858; 49452-3657; 30142-048; 80425-0154; 68071-3388; 58602-843; 70934-195; 60760-596; 25000-062; 72288-500; 53041-638; 72189-001; 69848-012; 37808-221; 50269-000; 43353-391; 53746-132; 70729-291; 80425-0047; 67091-141; 66715-6920; 53002-5711; 55319-817; 42708-006; 66267-964; 50844-393; 55700-445; 68210-4140; 68788-8148; 0113-1212; 42681-0026; 0113-7619; 49580-4560; 69452-262; 0904-5309; 36800-745; 0904-5855; 53002-3010; 55111-683; 42543-966; 59088-756; 70729-002; 41250-726; 58624-6002; 55910-651; 69842-649; 65162-466; 36800-660; 0573-0191; 68998-111; 25000-114; 62011-0399; 61919-621; 76420-980; 50090-2548; 37808-699; 59651-362; 0904-5853; 0363-1521; 60760-941; 70000-0571; 68071-3053; 62207-355; 54473-308; 81522-521; 56062-404; 0363-0291; 30142-965; 64380-807; 0363-0743; 70000-0360; 50844-353; 21130-363; 49035-647; 42708-097; 11822-0231; 63868-779; 63868-428; 64024-002; 41520-745; 24385-058; 67091-348; 50580-230; 56062-604; 64380-808; 72789-186; 68071-5066; 11788-008; 55910-604; 61919-960; 76282-712; 59779-604; 62207-365; 45802-057; 69452-302; 50090-5160; 53041-639; 10267-3846; 53187-199; 49035-601; 63868-773; 67877-319; 36800-753; 41250-293; 71335-0458; 33992-0752; 59779-647; 70000-0176; 0573-0175; 0573-1769; 64092-204; 59556-855; 55910-897; 60760-597; 60760-529; 67751-146; 0573-0166; 53746-140; 69452-260; 11673-255; 66220-284; 41163-604; 63940-393; 0121-1828; 50090-5819; 41163-710; 11822-8925; 69848-011; 50090-2597; 51293-844; 53041-572; 37808-023; 69135-0001; 51672-2138; 41520-166; 47682-683; 68210-0200; 68210-4192; 67835-0019; 68071-4952; 0472-1760; 50090-3977; 21130-396; 71610-202; 11822-0589; 53746-466; 0113-7604; 72288-517; 11014-0004; 69168-368; 0113-0166; 55910-197; 69842-521; 43063-847; 0904-7914; 67751-165; 63941-301; 68071-4306; 0363-9611; 57243-291; 70518-0176; 0573-0171; 0363-0221; 68071-4217; 58624-7005; 53943-112; 0113-4021; 72036-109; 41163-897; 53943-111; 68071-3125; 69842-489; 41520-647; 60760-604; 63868-427; 46122-548; 69842-329; 63940-292; 82179-001; 59556-805; 50090-5444; 53002-3011; 69452-263; 54348-830; 42543-964; 0113-0604; 68391-604; 66715-9739; 49348-706; 72288-660; 50090-4331; 66715-9812; 67091-321; 47682-609; 51407-371; 50090-2670; 55319-150; 51293-845; 42291-428; 50844-352; 41163-116; 43063-914; 41520-685; 71610-550; 68071-5154; 68016-944; 55910-521; 72476-111; 11788-002; 68016-943; 76003-0557; 50844-438; 53746-137; 66715-6707; 49035-660; 70000-0175; 55319-661; 50580-409; 50090-5433; 30142-513; 50844-269; 0363-1517; 67296-1611; 55301-745; 68196-980; 55670-850; 41250-897; 0573-0179 |
| Synonyms |
Ibuprofen | alpha-Methyl-4-(2-methylpropyl)benzeneacetic Acid | Ibumetin | Ibuprofen, (+-)-Isomer | Ibuprofen, (R)-Isomer | Ibuprofen, (S)-Isomer | Ibuprofen, Aluminum Salt | Ibuprofen, Calcium Salt | Ibuprofen, Copper (2+) Salt | Ibuprofen, Magnesium Salt | Ibuprofen, Potassium Salt | Ibuprofen, Sodium Salt | Ibuprofen, Zinc Salt | Ibuprofen-Zinc | Ibuprofen Zinc | Motrin | Nuprin | Rufen | Salprofen | Trauma-Dolgit Gel | Trauma Dolgit Gel | Brufen |
