Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dichlorphenamide
Drug ID BADD_D00652
Description A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Indications and Usage For adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure
Marketing Status Prescription; Discontinued
ATC Code S01EC02
DrugBank ID DB01144
KEGG ID D00518
MeSH ID D004005
PubChem ID 3038
TTD Drug ID D0J4GO
NDC Product Code 59651-223; 72065-001; 58159-071; 73435-011; 71090-001; 51672-4177
Synonyms Dichlorphenamide | Dichlofenamide | Diclofenamid | Glauconide | Daranide
Chemical Information
Molecular Formula C6H6Cl2N2O4S2
CAS Registry Number 120-97-8
SMILES C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Blood uric acid increased13.02.04.001--Not Available
Body temperature increased13.15.01.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Conversion disorder19.24.01.001--Not Available
Depression19.15.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Electrolyte imbalance14.05.01.002--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hyperchloraemia14.05.08.001--Not Available
Hyperuricaemia14.09.01.003--
Hypokalaemia14.05.03.002--
Leukopenia01.02.02.001--Not Available
Metabolic acidosis14.01.01.003--Not Available
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
Nervousness19.06.02.003--Not Available
Paraesthesia17.02.06.005--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
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