Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ovarian cancer
ADR ID BADD_A03237
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.12      Reproductive neoplasms female malignant and unspecified
16.12.04      Ovarian neoplasms malignant (excl germ cell)
16.12.04.001      Ovarian cancer
21      Reproductive system and breast disorders
21.11      Ovarian and fallopian tube disorders
21.11.01      Ovarian and fallopian tube cysts and neoplasms
21.11.01.003      Ovarian cancer
Description Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. [MeSH]
MedDRA Code 10033128
MeSH ID D010051; D010051; D010051
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ca ovary | Cancer of ovary | Malignant neoplasm of ovary | Ovarian cancer | Ovarian cancer NOS | Ovarian carcinoma | Ovarian carcinosarcoma | Ovarian Neoplasms | Neoplasm, Ovarian | Ovarian Neoplasm | Ovary Neoplasms | Neoplasm, Ovary | Neoplasms, Ovary | Ovary Neoplasm | Neoplasms, Ovarian | Ovary Cancer | Cancer, Ovary | Cancers, Ovary | Ovary Cancers | Ovarian Cancer | Cancer, Ovarian | Cancers, Ovarian | Ovarian Cancers | Cancer of Ovary | Cancer of the Ovary
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformP42338T05031
RAC-alpha serine/threonine-protein kinaseP31749T67619
Rho-associated protein kinase 1Q13464T51282
Signal transducer and activator of transcription 3P40763T29130
Transforming protein RhoAP61586T96736
Tyrosine-protein kinase JAK2O60674T08391
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000053%
BADD_D00088Altretamine--
BADD_D00151Apixaban0.000207%
BADD_D00156Apremilast--
BADD_D00195Azathioprine0.000375%
BADD_D00285Bosentan0.000175%
BADD_D00364Carboplatin0.000278%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00511Clozapine0.008042%
BADD_D00528Conjugated estrogens--
BADD_D00589Dasatinib0.000278%
BADD_D00680Dimethyl fumarate0.001435%
BADD_D00699Docetaxel--
BADD_D00723Doxorubicin0.000417%
BADD_D00785Epirubicin hydrochloride--
BADD_D00793Equilin sulfate--
BADD_D00820Esterified estrogens--
BADD_D00821Estradiol--
BADD_D00822Estradiol acetate--
BADD_D00823Estradiol cypionate--
BADD_D00824Estradiol hemihydrate--
BADD_D00825Estradiol valerate--
BADD_D00830Estrofen--
BADD_D00831Estrogens--
BADD_D00832Estrogens conjugated synthetic a--
BADD_D00833Estrogens conjugated synthetic b--
BADD_D00834Estrone--
BADD_D00835Estrone sulfate--
BADD_D00836Estropipate--
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