Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01695Peginterferon alfa-2a--
BADD_D01696Peginterferon alfa-2b--
BADD_D01700Pembrolizumab--
BADD_D01701Pemetrexed--
BADD_D01702Pemetrexed disodium--
BADD_D01706Penbutolol--
BADD_D01707Penbutolol sulfate--
BADD_D01708Penciclovir--
BADD_D01710Penicillin g--
BADD_D01711Penicillin g benzathine--
BADD_D01713Penicillin g procaine--
BADD_D01717Pentamidine--
BADD_D01730Pentostatin--
BADD_D01733Perampanel--
BADD_D01734Perflutren--
BADD_D01737Perhexiline--
BADD_D01740Perindopril erbumine--
BADD_D01741Perindoprilat--
BADD_D01744Pertuzumab--
BADD_D01750Phenelzine0.000062%
BADD_D01751Phenelzine sulfate--
BADD_D01754Phenoxybenzamine--
BADD_D01755Phenoxybenzamine hydrochloride--
BADD_D01756Phentermine0.000731%
BADD_D01765Phenytoin--
BADD_D01767Phosphonatoformate--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01775Pinaverium bromide--
BADD_D01776Pindolol--
BADD_D01777Pioglitazone--
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ADReCS-Target
ADR Term Drug Name Target