Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phenelzine sulfate
Drug ID BADD_D01751
Description Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder.[A15753] It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Indications and Usage A nonendogenous depression is characterized by a disturbance in mood and general outlook. The physical symptoms tend to be less severe and it often occurs in response to stressful life events that keep occurring over a large period of time generating a continuous stress in the daily living.[A31924]
Marketing Status Prescription
ATC Code N06AF03
DrugBank ID DB00780
KEGG ID D00505
MeSH ID D010624
PubChem ID 61100
TTD Drug ID D0P9AC
NDC Product Code 46016-1562; 59762-0119; 60862-004; 43386-360; 0071-0350
Synonyms Phenelzine | beta-Phenylethylhydrazine | beta Phenylethylhydrazine | Fenelzin | Phenethylhydrazine | 2-Phenethylhydrazine | 2 Phenethylhydrazine | Phenelzine Sulfate | Sulfate, Phenelzine | Nardelzine | Nardil
Chemical Information
Molecular Formula C8H14N2O4S
CAS Registry Number 156-51-4
SMILES C1=CC=C(C=C1)CCNN.OS(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Blood creatine phosphokinase increased13.04.01.001--
Coma17.02.09.001--Not Available
Constipation07.02.02.001--
Delirium19.13.02.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Euphoric mood19.04.02.006--
Fatigue08.01.01.002--
Feeling jittery08.01.09.016--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Glaucoma06.03.01.002--
Headache17.14.01.001--
Hepatocellular injury09.01.07.008--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypernatraemia14.05.04.001--
Hyperpyrexia08.05.02.002--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersomnia19.02.05.001; 17.15.01.001--
Hypoxia22.02.02.003--
Insomnia19.02.01.002; 17.15.03.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Leukopenia01.02.02.001--Not Available
Mania19.16.02.002--
Metabolic acidosis14.01.01.003--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Muscle twitching15.05.03.005--Not Available
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