Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Penciclovir
Drug ID BADD_D01708
Description Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Indications and Usage Used to treat recurrent cold sores on the lips and face from various herpesvirus invections.
Marketing Status Prescription
ATC Code D06BB06; J05AB13
DrugBank ID DB00299
KEGG ID D05407
MeSH ID C053539
PubChem ID 135398748
TTD Drug ID D07BYK
NDC Product Code 67835-0010; 69875-8004; 0378-9720; 29902-0021; 70600-022; 65015-899; 63310-2500; 46708-932
Synonyms penciclovir | 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine | penciclovir, monosodium salt | BRL 39123 | BRL-39123 | Penciclovir Visfarm | Denavir | Vectavir | penciclovir, monosodium salt, monohydrate
Chemical Information
Molecular Formula C10H15N5O3
CAS Registry Number 39809-25-1
SMILES C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaemia01.03.02.001--
Anaesthesia17.02.07.002--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Application site reaction08.02.01.006; 12.07.01.006--Not Available
Asthenia08.01.01.001--Not Available
Condition aggravated08.01.03.004--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Delirium19.13.02.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dysgeusia17.02.07.003; 07.14.03.001--
Dysmenorrhoea21.01.01.002--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gastrointestinal pain07.01.05.005--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypersensitivity vasculitis24.05.02.012; 23.06.02.005; 10.02.02.017; 01.01.04.008--Not Available
Hypoaesthesia17.02.06.023--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Liver function test abnormal13.03.01.013--Not Available
Local swelling08.01.03.013--Not Available
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