Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pindolol
Drug ID BADD_D01776
Description Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension.[L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia.[A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Indications and Usage For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Marketing Status Prescription; Discontinued
ATC Code C07AA03
DrugBank ID DB00960
KEGG ID D00513
MeSH ID D010869
PubChem ID 4828
TTD Drug ID D0F2PO
NDC Product Code 64330-109; 49169-0006; 29033-029; 57664-656; 29033-028; 0378-0127; 62559-560; 72789-100; 70771-1134; 62559-561; 70771-1135; 76385-131; 70710-1064; 72789-099; 70710-1063; 76385-132; 57664-655; 0378-0052
Synonyms Pindolol | Prindolol | Visken | LB-46 | LB 46 | LB46
Chemical Information
Molecular Formula C14H20N2O2
CAS Registry Number 13523-86-9
SMILES CC(C)NCC(COC1=CC=CC2=C1C=CN2)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Aggression19.05.01.001--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Atrioventricular block02.03.01.002--Not Available
Atrioventricular block second degree02.03.01.005--
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac failure02.05.01.001--
Cardiac failure congestive02.05.01.002--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Conduction disorder02.03.01.008--
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Eye irritation06.04.05.003--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
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