Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phenoxybenzamine hydrochloride
Drug ID BADD_D01755
Description An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Indications and Usage For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Marketing Status Prescription
ATC Code C04AX02
DrugBank ID DB00925
KEGG ID D00507
MeSH ID D010643
PubChem ID 5284441
TTD Drug ID D0X2DK
NDC Product Code 76339-143; 49452-5214; 59212-001; 49884-038; 59651-298; 71292-123; 51927-0031; 47621-309; 14096-114; 76438-003; 60219-1502; 72969-057; 59981-023; 0054-0349; 58159-044; 66993-066; 58032-1014
Synonyms Phenoxybenzamine | Phenoxybenzamine Hydrochloride | Hydrochloride, Phenoxybenzamine | Dibenzyline | Dibenzylin | Dibenyline | Dibenylene | Dibenziran | Dibenzyran
Chemical Information
Molecular Formula C18H22ClNO.ClH
CAS Registry Number 63-92-3
SMILES CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ejaculation delayed21.03.01.001--Not Available
Fatigue08.01.01.002--
Miosis17.02.11.002; 06.05.03.003--Not Available
Nasal congestion22.04.04.001--
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Gastrointestinal tract irritation07.08.03.008--Not Available
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