| Pharmaceutical Information |
| Drug Name |
Pinaverium bromide |
| Drug ID |
BADD_D01775 |
| Description |
Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable bowel syndrome (IBS) [A19702]. Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets. Although it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries including Canada. |
| Indications and Usage |
Indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) associated with abdominal pain, bowel disturbances and intestinal discomfort, as well as the treatment of symptoms related to functional disorders of the biliary tract. |
| Marketing Status |
Not Available |
| ATC Code |
A03AX04 |
| DrugBank ID |
DB09090
|
| KEGG ID |
D07094
|
| MeSH ID |
C013199
|
| PubChem ID |
40703
|
| TTD Drug ID |
D0J1NQ
|
| NDC Product Code |
52128-175; 65372-1135 |
| Synonyms |
pinaverium | Dicetel | pinaverium bromide | 4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium bromide | Eldicet |
|
| Chemical Information |
| Molecular Formula |
C26H41Br2NO4 |
| CAS Registry Number |
53251-94-8 |
| SMILES |
CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C.[Br-] |
| Chemical Structure |
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| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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