Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01071Histamine--
BADD_D01073Histrelin--
BADD_D01084Hydrocodone--
BADD_D01086Hydrocortisone0.000886%
BADD_D01087Hydrocortisone acetate--
BADD_D01095Hydrogen iodide--
BADD_D01096Hydromorphone--
BADD_D01102Hydroxybutanoic acid--
BADD_D01103Hydroxychloroquine--
BADD_D01104Hydroxychloroquine sulfate--
BADD_D01106Hydroxyprogesterone--
BADD_D01110Hydroxyurea--
BADD_D01114Hyoscyamine--
BADD_D01115Hyoscyamine sulfate--
BADD_D01117Ibandronic acid--
BADD_D01118Ibritumomab tiuxetan--
BADD_D01119Ibrutinib0.036209%
BADD_D01120Ibuprofen--
BADD_D01124Icodextrin--
BADD_D01130Idelalisib--
BADD_D01132Idursulfase--
BADD_D01133Ifosfamide--
BADD_D01134Iloperidone--
BADD_D01136Imatinib0.027691%
BADD_D01137Imatinib mesylate--
BADD_D01138Imiglucerase--
BADD_D01139Imipramine--
BADD_D01140Imipramine hydrochloride--
BADD_D01141Imipramine pamoate--
BADD_D01142Imiquimod0.006409%
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ADReCS-Target
ADR Term Drug Name Target