| ADR Ontology |
| ADR Term |
Eye movement disorders |
| ADR ID |
BADD_A01587 |
| ADR Hierarchy |
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| Description |
Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240) [MeSH] |
| MedDRA Code |
10015951 |
| MeSH ID |
D015835
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ADR Severity Grade (FAERS)
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Not Available
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ADR Severity Grade (CTCAE)
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| Synonym |
| Ocular Motility Disorders | Ocular Motility Disorder | Eye Movement Disorders | Eye Movement Disorder | Eye Motility Disorders | Eye Motility Disorder | Convergence Excess | Convergence Excesses | Excess, Convergence | Convergence Insufficiency | Convergence Insufficiencies | Insufficiencies, Convergence | Insufficiency, Convergence | Cyclophoria | Cyclophorias | Internuclear Ophthalmoplegia | Internuclear Ophthalmoplegias | Ophthalmoplegia, Internuclear | Ophthalmoplegias, Internuclear | Spasm of Conjugate Gaze | Conjugate Gaze Spasm | Conjugate Gaze Spasms | Gaze Spasms, Conjugate | Opsoclonus | Parinaud Syndrome | Syndrome, Parinaud | Parinaud's Syndrome | Parinauds Syndrome | Syndrome, Parinaud's | Paroxysmal Ocular Dyskinesia | Dyskinesia, Paroxysmal Ocular | Dyskinesias, Paroxysmal Ocular | Ocular Dyskinesia, Paroxysmal | Ocular Dyskinesias, Paroxysmal | Paroxysmal Ocular Dyskinesias | Pseudoophthalmoplegia | Pseudoophthalmoplegias | Skew Deviation | Deviation, Skew | Deviations, Skew | Skew Deviations | Smooth Pursuit Deficiency | Deficiencies, Smooth Pursuit | Pursuit Deficiencies, Smooth | Pursuit Deficiency, Smooth | Smooth Pursuit Deficiencies | Deficiency, Smooth Pursuit | Brown Tendon Sheath Syndrome | Syndrome, Brown's Tendon Sheath | Tendon Sheath Syndrome of Brown | Brown's Tendon Sheath Syndrome | Ocular Torticollis |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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