Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01500Morphine tincture--
BADD_D01501Moxifloxacin--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid--
BADD_D01510Nabilone--
BADD_D01511Nabumetone--
BADD_D01512Nadolol--
BADD_D01513Nafarelin--
BADD_D01527Naltrexone--
BADD_D01528Naltrexone hydrochloride--
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
BADD_D01535Naratriptan0.007407%
BADD_D01536Naratriptan hydrochloride--
BADD_D01537Natalizumab--
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01549Nelarabine--
BADD_D01558Nexium--
BADD_D01560Nicardipine--
BADD_D01562Nicorandil--
BADD_D01564Nicotine--
BADD_D01566Nifedipine--
BADD_D01567Nilotinib0.007555%
BADD_D01568Nilutamide--
BADD_D01571Nitazoxanide--
BADD_D01572Nitisinone0.018974%
BADD_D01573Nitrazepam--
BADD_D01576Nitrofurantoin--
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